Evidence map›Paper›PMID 32147138›Full record

ArticleThe journal of allergy and clinical immunology. In practice2020

Childhood Origins of Adult Lung Disease as Opportunities for Prevention.

Torie Grant, Emily P Brigham, Meredith C McCormack

Open access · greenAbstract read
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 64 citations in OpenAlex.

  1. Early-life respiratory syncytial virus infection and asthma.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  2. Allergic sensitization and respiratory infection in infancy-Too early for two-hits on lung function?Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Asthma Phenotypes and Biomarkers.Respiratory care · 2025
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Childhood Air Pollution Exposure Associated with Self-reported Bronchitic Symptoms in Adulthood.American journal of respiratory and critical care medicine · 2024
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Torie GrantDivision of Pediatric Allergy/Immunology, Johns Hopkins University School of Medicine, Baltimore, Md.
Emily P BrighamDivision of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Md.
Meredith C McCormackDivision of Pulmonary and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Md. Electronic address: mmccor16@jhmi.edu.
Johns Hopkins University · US

Funding

The role of obesity in biological responses to particulate matter in miceP50ES018176 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI HANSEL, NADIA N · 2015 to 2019
$4.8M
The Environmental Assessments Core (FSC)P50MD010431 · NIMHD · JOHNS HOPKINS UNIVERSITY · PI HANSEL, NADIA N · 2015 to 2019
$3.5M
Relationship Between Indoor Ultrafine Particle Exposure and Respiratory Morbidity, Inflammation, and Oxidative Stress in Children with AsthmaK23ES029105 · NIEHS · UNIVERSITY OF BRITISH COLUMBIA · PI BRIGHAM, EMILY · 2019 to 2022
$755k
NIEHS NIH HHS K23 ES029105NIEHS NIH HHS P50 ES018176NIMHD NIH HHS P50 MD010431
6 · The paper itself

Abstract

Prenatal and childhood exposures have been shown to impact lung development, lung function trajectory, and incidence and prevalence of respiratory disease. Early life may serve as a window of susceptibility to such exposures, with the potential to influence lifelong respiratory health. Risk factors encountered in early life with potentially durable impact on lung health include prematurity, respiratory viral illness, allergen sensitization and exposure, tobacco use and exposure, indoor and outdoor pollution, diet, and obesity. These exposures vary in the extent to which they are modifiable, and interventions aimed at reducing harmful exposures range from individual-level behavior modification to policy initiatives implemented to promote population health. For many exposures, including tobacco-related exposures, multilevel interventions are needed. Future research is needed to provide insight as to early-life interventions to promote optimal lung growth and prevent development of chronic respiratory disease. Clinicians should play an active role, assisting individual patients in avoiding known detrimental exposures including maternal smoking during pregnancy and initiation of active smoking. Clinicians can be empowered by evidence to support policies promoting reduction of population-level risk factors, such as restriction on electronic cigarette sales and legislation to uphold air quality standards, to encourage attainment of maximal lung function and reduce risk of chronic lung disease.

Indexed as

Electronic Nicotine Delivery SystemsPulmonary Disease, Chronic ObstructiveTobacco Smoke PollutionAdultChildFemaleHumansLungPregnancySmokingTobacco Smoke PollutionAsthma preventionAsthma risk factorsCOPD preventionCOPD risk factorsLung function trajectory

Identifiers

PMID32147138
PMCPMC7653544
OpenAlexW3012166835

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.