Observational studyRheumatology international2020
Applicability of shear wave elastography for the evaluation of skin strain in systemic sclerosis.
Observational study in Rheumatology international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- High-resolution ultrasound imaging of skin involvement in systemic sclerosis: a systematic review.Rheumatology international · 2021Pooled it
- Effects of occupational therapy on hand function in patients with systemic sclerosis: a randomized controlled trial.Rheumatology international · 2025Trial
- Shear Wave Elastography for Non-Invasive Assessment of Skin Involvement in Systemic Sclerosis.Diagnostics (Basel, Switzerland) · 2026Article
- Multimodal Non-Invasive Skin Imaging in Dermatology: Current Modalities, Clinical Applications, and Future Integration.Diagnostics (Basel, Switzerland) · 2026Review
- Increased thyroid stiffness without volume change in systemic sclerosis: a case-control study using two-dimensional shear wave elastography.Rheumatology international · 2026Article
- Scleredema of Buschke in a paediatric patient: a novel non-invasive diagnostic and monitoring approach using line-field confocal optical coherence tomography and shear wave elastography.Rheumatology (Oxford, England) · 2026Article
- Asynchronous, semi-reverberant elastography.Optica · 2024Article
- Skin Ultrasound Assessment of Patients with Systemic Scleroderma-An Observational Study.Journal of personalized medicine · 2024Article
- [Methodology and clinical use of superb microvascular imaging in assessing micro-circulation changes of fingertips in systemic sclerosis].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2023Article
- Salivary ultrasonography and histopathologic evaluation of secondary Sjögren's syndrome in rheumatoid arthritis patients.Scientific reports · 2023Article
- Subcutaneous immunoglobulin therapy for refractory skin thickening in rapidly progressive systemic sclerosis: A case report and literature review.Journal of scleroderma and related disorders · 2023Review
- The value of shear wave elastography in diagnosis and assessment of systemic sclerosis.Rheumatology advances in practice · 2023Article
- Role of shear wave elastography ultrasound in patients with systemic sclerosis.Journal of ultrasound · 2022Article
- Shear wave elastography as a potential additional diagnostic tool in primary Sjögren's syndrome: an observational study.Rheumatology international · 2022Observational
- Updated Role of High-frequency Ultrasound in Assessing Dermatological Manifestations in Autoimmune Skin Diseases.Acta dermato-venereologica · 2022Review
- Elastography as a possible useful method of assessment of skin involvement in systemic sclerosis.Postepy dermatologii i alergologii · 2022Article
- The role of ultrasound in systemic sclerosis: On the cutting edge to foster clinical and research advancement.Journal of scleroderma and related disorders · 2021Review
- Imaging in Diagnosis of Systemic Sclerosis.Journal of clinical medicine · 2021Review
- The Updated Role of Ultrasound in Assessing Dermatological Manifestations in Systemic Sclerosis.Open access rheumatology : research and reviews · 2021Review
- How to perform high ultrasound examination of skin involvement among patients with systemic sclerosis - proposition of a unified protocol.Reumatologia · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The assessment of skin fibrosis is vital for the diagnosis and monitoring of treatment in the systemic sclerosis (SSc)-a severe autoimmune disease. The elastography is a technique of skin fibrosis assessment through the evaluation of skin strain. We compared the efficacy of the shear wave elastography (SWE) and commonly used modified Rodnan skin score (RSS) in skin fibrosis assessment in SSc. The study included 40 SSc patients and 28 healthy individuals, with the exclusion of individuals with other skin/autoimmune diseases. Skin thickness using RSS and skin strain using SWE were assessed in the same 20 body localizations. Subjects' informed consent and the bioethics committee approval were obtained. Elastographic skin strain correlated positively with both partial and overall RSS values, with strong positive correlation (r ≥ 0.75) for hands and fingers localizations in particular. In SSc patients with normal RSS values, the elastographic strain was significantly higher than in healthy controls. Elastographic strain of fingers' skin evaluated in SWE is highly accurate for distinguishing SSc patients (sensitivity 0.897-0.923, specificity 0.929-0.964, positive predictive value 0.946-0.973, negative predictive value 0.867-0.900). ESW results are substantially more reproducible than those of RSS examination (intraclass correlation coefficients: 0.987 vs. 0.941). The shear wave elastography is more reproducible and has higher sensitivity than RSS in the evaluation of skin condition in SSc, especially in case of changes non-detectable on physical evaluation, indicating it might become a useful tool in SSc diagnosis.
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