ReviewCurrent opinion in neurobiology2020
Aversion hot spots in the dopamine system.
Review in Current opinion in neurobiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 87 citations in OpenAlex.
- Article
- Dorsal Raphe VIP Neurons Are Critical for Survival-Oriented Vigilance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Effect of Testosterone on Maintenance of Morphine-induced Conditioned Place Preference: Androgen and μ-opioid Receptor Gene Expressions in PFC and NAc of Rats.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2026Article
- Sense of agency and decision making.Frontiers in psychology · 2026Article
- Nucleus accumbens DRD2 receptor agonism attenuates escape behavior.Frontiers in neuroscience · 2026Article
- Review
- Recruitment of specific dopamine neuron sub-circuits by opioids.Addiction neuroscience · 2025Article
- VTA dopamine neuron activity produces spatially organized value representations.bioRxiv : the preprint server for biology · 2025Article
- A hardwired neural circuit for temporal difference learning.bioRxiv : the preprint server for biology · 2025Article
- Functional connectivity between the nucleus accumbens and amygdala underlies avoidance learning during adolescence: Implications for developmental psychopathology.Development and psychopathology · 2025Article
- Presynaptic Mu Opioid Receptors Suppress the Functional Connectivity of Ventral Tegmental Area Dopaminergic Neurons with Aversion-Related Brain Regions.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Cannabidiol abrogates cue-induced anxiety associated with normalization of mitochondria-specific transcripts and linoleic acid in the nucleus accumbens shell.Molecular psychiatry · 2025Article
- Region-specific nucleus accumbens dopamine signals encode distinct aspects of avoidance learning.Current biology : CB · 2025Article
- Dopamine induces fear extinction by activating the reward-responding amygdala neurons.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Translating stress systems: corticotropin releasing factor, its receptors, and the dopamine system in nonhuman primate models.Genomic psychiatry : advancing science from genes to society · 2025Article
- Dopamine prediction error signaling in a unique nigrostriatal circuit is critical for associative fear learning.Nature communications · 2025Article
- Establishing functionally segregated dopaminergic circuits.Trends in neurosciences · 2025Review
- How Dopamine Enables Learning from Aversion.Current opinion in behavioral sciences · 2025Article
- Molecular characterization of chicken DA systems reveals that the avian personality gene,Frontiers in neuroanatomy · 2025Article
- Representation of Anticipated Rewards and Punishments in the Human Brain.Annual review of psychology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Through the development of optogenetics and other viral vector-based technologies, our view of the dopamine system has substantially advanced over the last decade. In particular, progress has been made in the reclassification of dopamine neurons based on subtypes displaying specific projections, which are associated with different features at the anatomical, molecular and behavioral level. Together, these discoveries have raised the possibility that individual groups of dopamine cells make a unique contribution to the processing of reward and aversion. Here, we review recent studies that have identified non-canonical dopamine pathways that are excited in response to aversive stimuli, including dopamine projections to the ventromedial shell of the nucleus accumbens, prefrontal cortex, tail of the striatum, and amygdala.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.