Evidence map›Paper›PMID 32146159›Full record

ArticleCell calcium2020

TRPM7 activation potentiates SOCE in enamel cells but requires ORAI.

Guilherme H Souza Bomfim, Veronica Costiniti, Yi Li, Youssef Idaghdour, Rodrigo S Lacruz

Open access · greenAbstract read
In one paragraph

Article in Cell calcium, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Mathematical Modeling of Calcium Dynamics in Ameloblasts.Calcified tissue international · 2026
    Article
  4. Mechanosensitive Piezo1 Channels in Enamel Cells.Calcified tissue international · 2026
    Article
  5. Roles of calcium in ameloblasts during tooth development: A scoping review.Journal of Taibah University Medical Sciences · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Mitochondria modulate ameloblast CaFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
    Article
  10. Article
  11. TRPM7-Mediated Calcium Transport in HAT-7 Ameloblasts.International journal of molecular sciences · 2021
    Article
  12. Review
  13. Mapping TRPM7 Function by NS8593.International journal of molecular sciences · 2020
    Review
  14. Article
  15. The Ion Channel and GPCR Toolkit of Brain Capillary Pericytes.Frontiers in cellular neuroscience · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Guilherme H Souza BomfimDepartment of Basic Science and Craniofacial Biology, New York University College of Dentistry, New York, NY, 10010, USA.
Veronica CostinitiDepartment of Basic Science and Craniofacial Biology, New York University College of Dentistry, New York, NY, 10010, USA.
Yi LiDepartment of Basic Science and Craniofacial Biology, New York University College of Dentistry, New York, NY, 10010, USA.
Youssef IdaghdourBiology Program, Division of Science and Mathematics, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates.
Rodrigo S LacruzDepartment of Basic Science and Craniofacial Biology, New York University College of Dentistry, New York, NY, 10010, USA. Electronic address: rodrigo.lacruz@nyu.edu.
New York University · USNew York University Abu Dhabi · AE

Funding

Redox and Ca2+ signaling regulation of enamel mineralizationR01DE027679 · NIDCR · NEW YORK UNIVERSITY · PI Rodrigo S. Lacruz · 2018 to 2026
$3.3M
Calcium Control of Enamel DevelopmentR01DE025639 · NIDCR · NEW YORK UNIVERSITY · PI LACRUZ, RODRIGO S. · 2016 to 2020
$2.0M
NIDCR NIH HHS R01 DE025639NIDCR NIH HHS R01 DE027679
6 · The paper itself

Abstract

Calcium (Ca

Indexed as

AmeloblastsAnimalsCalciumCell LineDental EnamelFemaleMaleMiceNaltrexoneORAI1 ProteinRats, Sprague-DawleyRNA, Small InterferingTRPM Cation ChannelsCalciumNaltrexonenaltrindole benzofuranORAI1 ProteinRNA, Small InterferingTrpm7 protein, ratTRPM Cation ChannelsCa(2+) signalingCRAC channelsEnamel cellsSOCETRPM7 channels

Identifiers

PMID32146159
PMCPMC7202080
OpenAlexW3006800806

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.