Evidence map›Paper›PMID 32145992›Full record

ArticleAmerican journal of infection control2020

Association between Clostridioides difficile infection and multidrug-resistant organism colonization or infection among hospitalized adults: A case-control study.

Eisha Jain, Jae H Shin, Kristen M Wells, Aaron F Pannone, Paige P Hornsby, Cirle A Warren

Open access · greenAbstract read
In one paragraph

Article in American journal of infection control, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.0field-weighted citation impact, top 63% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Eisha JainDepartment of Public Health Sciences, University of Virginia, Charlottesville, VA.
Jae H ShinDivision of Infectious Diseases and International Health, University of Virginia School of Medicine, Charlottesville, VA.
Kristen M WellsDepartment of Public Health Sciences, University of Virginia, Charlottesville, VA.
Aaron F PannoneDepartment of Public Health Sciences, University of Virginia, Charlottesville, VA.
Paige P HornsbyDepartment of Public Health Sciences, University of Virginia, Charlottesville, VA.
Cirle A WarrenDivision of Infectious Diseases and International Health, University of Virginia School of Medicine, Charlottesville, VA. Electronic address: ca6t@hscmail.mcc.virginia.edu.
University of Virginia · US

Funding

Alanyl-glutamine supplementation of standard treatment for C. difficile infectionR01AI145322 · NIAID · UNIVERSITY OF VIRGINIA · PI WARREN, CIRLE ALCANTARA · 2020 to 2024
$4.0M
Effects of alanyl-glutamine supplementation on C. difficile associated diarrheaR34AI110382 · NIAID · UNIVERSITY OF VIRGINIA · PI WARREN, CIRLE ALCANTARA · 2014 to 2014
$237k
NIAID NIH HHS R01 AI145322NIAID NIH HHS R34 AI110382
6 · The paper itself

Abstract

Using an ambidirectional case-control study, we found that the odds of Clostridioides difficile infection (CDI) were 3.38 (P = .01) times higher for patients with multidrug-resistant organism (MDRO) colonization compared to those without. MDRO colonization or infection 1-12 months before CDI testing significantly increased risk of positive CDI diagnosis (odds ratio 4.71, P = .02 and odds ratio = 5.03, P = .05, respectively) independent of antibiotic use, age, and comorbidity status. MDRO colonization and infection are associated with CDI, most significantly if they precede CDI.

Indexed as

Clostridioides difficileClostridium InfectionsAdultCase-Control StudiesClostridioidesDrug Resistance, Multiple, BacterialHumansAntibiotic-associated diarrheaC. difficileMDRONosocomial infection

Identifiers

PMID32145992
PMCPMC9840385
OpenAlexW3009072534

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.