Evidence map›Paper›PMID 32145739›Full record

ArticleBMC pediatrics2020

Adolescent Interventions to Manage Self-Regulation in Type 1 Diabetes (AIMS-T1D): randomized control trial study protocol.

Alison L Miller, Sharon L Lo, Dana Albright, Joyce M Lee, Christine M Hunter, Katherine W Bauer, Rosalind King, Katy M Clark, Kiren Chaudhry, Niko Kaciroti and 2 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMC pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03688919 (Targeting Self-regulation to Promote Adherence and Health Behaviors in Children), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03688919 nacompletednot on this map

Targeting Self-regulation to Promote Adherence and Health Behaviors in Children

TypeinterventionalSponsorUniversity of MichiganRan2019 to 2021Enrolled88ConditionsSelf-regulation, Medication AdherenceArmsSelf-Regulation Intervention
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Barriers to Type 1 Diabetes Adherence in Adolescents.Journal of clinical medicine · 2024
    Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Alison L MillerDepartment of Health Behavior and Health Education, University of Michigan School of Public Health, 1415 Washington Heights, SPH I Room 3718, Ann Arbor, MI, 48109-2029, USA. alimill@umich.edu.ORCID 0000-0002-9866-0204
Sharon L LoDepartment of Health Behavior and Health Education, University of Michigan School of Public Health, 1415 Washington Heights, SPH I Room 3718, Ann Arbor, MI, 48109-2029, USA.
Dana AlbrightDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA.
Joyce M LeeDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA.
Christine M HunterOffice of Behavioral and Social Sciences Research, National Institutes of Health, Bethesda, MD, USA.
Katherine W BauerCenter for Human Growth and Development, University of Michigan, Ann Arbor, MI, USA.
Rosalind KingEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.
Katy M ClarkDepartment of Health Behavior and Health Education, University of Michigan School of Public Health, 1415 Washington Heights, SPH I Room 3718, Ann Arbor, MI, 48109-2029, USA.
Kiren ChaudhryDepartment of Health Behavior and Health Education, University of Michigan School of Public Health, 1415 Washington Heights, SPH I Room 3718, Ann Arbor, MI, 48109-2029, USA.
Niko KacirotiDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA.
Benjamin KatzDepartment of Human Development and Family Science, Virginia Tech, Blacksburg, VA, USA.
Emily M FredericksDepartment of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA.
University of Michigan · USMichigan Department of Health and Human Services · USNational Institutes of Health · USVirginia Tech · US

Funding

Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
Targeting Self-Regulation to Promote Adherence and Health Behaviors in ChildrenUH2HD087979 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MILLER, ALISON L · 2015 to 2017
$2.1M
Target self-regulation to promote adherence and health behaviors in childrenUH3HD087979 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FREDERICKS, EMILY MACDONALD, MILLER, ALISON L · 2018 to 2019
$2.1M
Training in Developmental Science to Improve Child Health and Well-BeingT32HD079350 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C · 2015 to 2019
$1.2M
Early Adversity, Biological Sensitivity, and Self-Regulation in Low-Income ChildrenF32HD100025 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LO, SHARON · 2019 to 2019
$57k
NICHD NIH HHS F32 HD100025NICHD NIH HHS T32 HD079350NICHD NIH HHS UH2 HD087979NICHD NIH HHS UH3 HD087979NIDDK NIH HHS P30 DK092926
6 · The paper itself

Abstract

backgroundSelf-regulation (SR), or the capacity to control one's thoughts, emotions, and behaviors in order to achieve a desired goal, shapes health outcomes through many pathways, including supporting adherence to medical treatment regimens. Type 1 Diabetes (T1D) is one specific condition that requires SR to ensure adherence to daily treatment regimens that can be arduous and effortful (e.g., monitoring blood glucose). Adolescents, in particular, have poor adherence to T1D treatment regimens, yet it is essential that they assume increased responsibility for managing their T1D as they approach young adulthood. Adolescence is also a time of rapid changes in SR capacity and thus a compelling period for intervention. Promoting SR among adolescents with T1D may thus be a novel method to improve treatment regimen adherence. The current study tests a behavioral intervention to enhance SR among adolescents with T1D. SR and T1D medical regimen adherence will be examined as primary and secondary outcomes, respectively.

methodsWe will use a randomized control trial design to test the impact of a behavioral intervention on three SR targets: Executive Functioning (EF), Emotion Regulation (ER), and Future Orientation (FO); and T1D medical regimen adherence. Adolescents with T1D (n = 94) will be recruited from pediatric endocrinology clinics and randomly assigned to treatment or control group. The behavioral intervention consists of working memory training (to enhance EF), biofeedback and relaxation training (to enhance ER), and episodic future thinking training (to enhance FO) across an 8-week period. SR and treatment regimen adherence will be assessed at pre- and post-test using multiple methods (behavioral tasks, diabetes device downloads, self- and parent-report). We will use an intent-to-treat framework using generalized linear mixed models to test our hypotheses that: 1) the treatment group will demonstrate greater improvements in SR than the control group, and 2) the treatment group will demonstrate better treatment regimen adherence outcomes than the control group. DISCUSSION: If successful, SR-focused behavioral interventions could improve health outcomes among adolescents with T1D and have transdiagnostic implications across multiple chronic conditions requiring treatment regimen adherence.

trial registrationClinicalTrials.gov: NCT03688919; registered September 28, 2018.

Indexed as

Blood Glucose Self-MonitoringDiabetes Mellitus, Type 1Self-ControlAdolescentAdultBlood GlucoseChildHumansMotivationRandomized Controlled Trials as TopicYoung AdultBlood GlucoseAdolescenceBehavioral interventionMedical regimen adherenceSelf-regulationType 1 diabetes

Identifiers

PMID32145739
PMCPMC7060523
OpenAlexW3011466309

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.