Evidence map›Paper›PMID 32145659›Full record

ArticleDrug and alcohol dependence2020

Validity of ICD-based algorithms to estimate the prevalence of injection drug use among infective endocarditis hospitalizations in the absence of a reference standard.

Kaitlin M McGrew, Hélène Carabin, Tabitha Garwe, S Reza Jafarzadeh, Mary B Williams, Yan Daniel Zhao, Douglas A Drevets

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kaitlin M McGrewDepartment of Biostatistics & Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, United States.
Hélène CarabinDepartment of Biostatistics & Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, United States; Département de pathologie et de microbiologie, Faculté de Médecine vétérinaire-Université de Montréal, Saint-Hyacinthe, Québec, J2S 2M2, Canada; Département de médecine sociale et preventive, École de Santé Publique, Université de Montréal, Montréal, Québec, H3N 1X9, Canada; Centre de Recherche en Santé Publique (CReSP), Université de Montréal, Montréal, Québec, Canada. Electronic address: helene.carabin@umontreal.ca.
Tabitha GarweDepartment of Biostatistics & Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, United States. Electronic address: Tabitha-Garwe@ouhsc.edu.
S Reza JafarzadehDepartment of Medicine, Boston University School of Medicine, Boston, MA 02118, United States. Electronic address: srjafarz@bu.edu.
Mary B WilliamsDepartment of Biostatistics & Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, United States; Department of Family and Community Medicine, OU-TU School of Community Medicine, Tulsa, OK 74135, United States. Electronic address: Mary-Williams@ouhsc.edu.
Yan Daniel ZhaoDepartment of Biostatistics & Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, United States. Electronic address: daniel-zhao@ouhsc.edu.
Douglas A DrevetsDepartment of Internal Medicine- Infectious Diseases, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, United States; Medical Services, Department of Veterans Affairs Medical Center, Oklahoma City, OK 73104, United States. Electronic address: Douglas-Drevets@ouhsc.edu.

Funding

Tracking and Evaluation CoreU54GM104938 · NIGMS · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI TIMOTHY M VANWAGONER · 2013 to 2026
$68.2M
Research and Evaluation Support Core Unit (RESCU Core)P30AR072571 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Michael Paul Lavalley · 2019 to 2026
$6.9M
Dynamic Treatment Regimens of Physical Activity for Persons with OsteoarthritisR21AR074578 · NIAMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI JAFARZADEH, S. REZA · 2019 to 2020
$411k
Effects of NSAIDs and non-NSAID Analgesics on Osteoarthritis OutcomesR03AG060272 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI JAFARZADEH, S. REZA · 2018 to 2019
$165k
NIAMS NIH HHS P30 AR072571NIAMS NIH HHS R21 AR074578NIA NIH HHS R03 AG060272NIGMS NIH HHS U54 GM104938
6 · The paper itself

Abstract

backgroundInternational Classification of Diseases (ICD) code algorithms are routinely used to estimate the frequency of illicit injection drug use (IDU)-associated hospitalizations in administrative health datasets despite a lack of evidence regarding their validity. We aimed to measure the sensitivity and specificity of ICD code algorithms used to estimate the prevalence of current/recent IDU among infective endocarditis (IE) hospitalizations without a reference standard.

methodsWe reviewed medical records of 321 patients aged 18-64 years old from an urban academic hospital with an IE diagnosis between 2007 and 2017. Diagnostic tests for IDU included self-reported IDU in medical records; a drug use, abuse and dependence (UAD) ICD algorithm; a Hepatitis C Virus (HCV) ICD algorithm; and a combination drug UAD/HCV ICD algorithm. Sensitivity, specificity and the misclassification error (ME)-adjusted IDU prevalence were estimated using Bayesian latent class models.

resultsThe combination algorithm had the highest sensitivity and lowest specificity. Sensitivity increased for the drug UAD algorithm in the ICD-10 period compared to the ICD-9 period. The ME-adjusted current/recent IDU prevalence estimated using the drug UAD and HCV algorithms was 23 % (95 % Bayesian credible interval: 16 %, 31 %). The unadjusted prevalence estimate from the drug UAD algorithm underestimated the ME-adjusted prevalence, while the combination algorithm overestimated it.

conclusionThe validity of ICD code algorithms for IDU among IE hospitalizations is imperfect and differs between ICD-9 and ICD-10. Commonly used ICD-based algorithms could lead to substantially biased prevalence estimates in IDU-associated hospitalizations when using administrative health data.

Indexed as

AlgorithmsAdolescentAdultBayes TheoremCross-Sectional StudiesEndocarditisFemaleHospitalizationHumansInternational Classification of DiseasesMaleMiddle AgedPrevalenceReference StandardsReproducibility of ResultsRetrospective StudiesBayesian analysisDiagnostic errorEndocarditisInternational Classification of DiseasesIntravenousSubstance abuseValidation studies

Identifiers

PMID32145659
PMCPMC9531330

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.