ArticleJournal of magnetic resonance imaging : JMRI2020
Quantitative MRI Reveals Microstructural Changes in the Upper Leg Muscles After Running a Marathon.
Article in Journal of magnetic resonance imaging : JMRI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 43 citations in OpenAlex.
- Effect of Daily OralNutrients · 2021Trial
- Standardizing quantitative muscle MRI: an inter-vendor evaluation in healthy adults.Magma (New York, N.Y.) · 2026Article
- Quantitative MRI evaluation of the effects of rest and different intensities of running on the recovery of thigh muscle microdamage after a half marathon.BMC sports science, medicine & rehabilitation · 2026Article
- Quantitative evaluation of cervical muscles in patients with degenerative cervical myelopathy using diffusion tensor imaging metrics.Bone & joint research · 2026Article
- Enhancement of muscle activation during squat exercise: evaluation with magnetic resonance imaging.European journal of applied physiology · 2025Article
- Sports Radiology: A Key Driver of Clinical Decision-Making.Diagnostics (Basel, Switzerland) · 2025Article
- Skeletal muscle elastic modulus in marathon distance runners.European journal of applied physiology · 2025Article
- Imaging of muscle injuries in soccer.Skeletal radiology · 2025Review
- From Voxels to Physiology: A Review of Diffusion Magnetic Resonance Imaging Applications in Skeletal Muscle.Journal of magnetic resonance imaging : JMRI · 2025Review
- Physiology and Pathophysiology of Marathon Running: A narrative Review.Sports medicine - open · 2025Review
- Investigating skeletal muscle micro-trauma with time-dependent diffusion and the random permeable barrier model.Scientific reports · 2024Article
- Effects of probiotic supplementation on 12 min run performance, mood management, body composition and gut microbiota in amateur marathon runners: A double-blind controlled trial.Journal of exercise science and fitness · 2024Article
- Changes in inflammatory edema and fat fraction of thigh muscles following a half-marathon in recreational marathon runners.European journal of sport science · 2024Article
- Compositional and Functional MRI of Skeletal Muscle: A Review.Journal of magnetic resonance imaging : JMRI · 2024Review
- A deep learning approach for fast muscle water T2 mapping with subject specific fat T2 calibration from multi-spin-echo acquisitions.Scientific reports · 2024Article
- MRI radiomics for hamstring strain injury identification and return to sport classification: a pilot study.Skeletal radiology · 2024Article
- Accelerated IVIM-corrected DTI in acute hamstring injury: towards a clinically feasible acquisition time.European radiology experimental · 2024Article
- Advanced quantitative magnetic resonance imaging of lower extremity muscle microtrauma after marathon: a mini review.Frontiers in sports and active living · 2024Review
- Model-based reconstructions for intravoxel incoherent motion and diffusion tensor imaging parameter map estimations.NMR in biomedicine · 2023Article
- [Imaging of muscle injuries in sports medicine].Radiologie (Heidelberg, Germany) · 2023Review
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe majority of sports-related injuries involve skeletal muscle. Unlike acute trauma, which is often caused by a single traumatic event leading to acute symptoms, exercise-induced microtrauma may remain subclinical and difficult to detect. Therefore, novel methods to detect and localize subclinical exercise-induced muscle microtrauma are desirable. PURPOSE: To assess acute and delayed microstructural changes in upper leg muscles with multiparametric quantitative MRI after running a marathon. STUDY TYPE: Longitudinal; 1-week prior, 24-48 hours postmarathon and 2-week follow-up POPULATION: Eleven men participants (age: 47-68 years). FIELD STRENGTH/SEQUENCE: Spin-echo echo planar imaging (SE-EPI) with diffusion weighting, multispin echo, Dixon, and fat-suppressed turbo spin-echo (TSE) sequences at 3T. MR datasets and creatine kinase (CK) concentrations were obtained at three timepoints. ASSESSMENT: Diffusion parameters, perfusion fractions, and quantitative (q)T STATISTICAL TESTS: Differences between timepoints in MR parameters were assessed with a multilevel linear mixed model and in CK concentrations with a Friedman test. Mean diffusivity (MD) and qT
resultsCK concentrations were elevated (1194 U/L [166-3906], P < 0.001) at 24-48 hours postmarathon and returned to premarathon values (323 U/L [56-2216]) at 2-week follow-up. Most of the MRI diffusion indices in muscles without acute injury changed at 24-48 hours postmarathon and returned to premarathon values at follow-up (MD, RD, and λ3; P < 0.006). qT DATA
conclusionMarathon running-induced microtrauma was detected with MRI in individual whole upper leg muscles and even more pronounced on local segments. LEVEL OF EVIDENCE: 2 TECHNICAL EFFICACY STAGE: 3 J. Magn. Reson. Imaging 2020;52:407-417.
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