Evidence map›Paper›PMID 32144584›Full record

Observational studySupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2020

Current knowledge regarding medication-related osteonecrosis of the jaw among different health professionals.

Wanessa Miranda-Silva, Marco Aurélio Montezuma, Bernar Monteiro Benites, Julia Stephanie Bruno, Felipe Paiva Fonseca, Eduardo Rodrigues Fregnani

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Awareness, perceptions and attitudes toward medication-related osteonecrosis of the jaw among physicians who treat osteoporosis.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  7. Article
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  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Wanessa Miranda-SilvaDepartment of Oral Medicine, Hospital Sírio-Libanês, Street Dona Adma Jafet 91-Bela Vista, São Paulo, SP, Brazil.
Marco Aurélio MontezumaDepartment of Oral Medicine, Hospital Sírio-Libanês, Street Dona Adma Jafet 91-Bela Vista, São Paulo, SP, Brazil.
Bernar Monteiro BenitesDepartment of Oral Medicine, Hospital Sírio-Libanês, Street Dona Adma Jafet 91-Bela Vista, São Paulo, SP, Brazil.
Julia Stephanie BrunoDepartment of Oral Medicine, Hospital Sírio-Libanês, Street Dona Adma Jafet 91-Bela Vista, São Paulo, SP, Brazil.
Felipe Paiva FonsecaDepartment of Oral Surgery and Pathology, School of Dentistry, Federal University of Minas Gerais, Street Professor Moacir Gomes de Freitas 688, Belo Horizonte, Brazil.
Eduardo Rodrigues FregnaniDepartment of Oral Medicine, Hospital Sírio-Libanês, Street Dona Adma Jafet 91-Bela Vista, São Paulo, SP, Brazil. eduardofregnani@me.com.ORCID http://orcid.org/0000-0001-5196-7631
Hospital Sírio-Libanês · BRUniversidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the current knowledge regarding medication-related osteonecrosis of the jaw (MRONJ); the adverse effects of anti-resorptive (AR) and anti-angiogenic (AA) drugs; strategies for MRONJ prevention and treatment; and perception of the dentist's role in assisting patients who use these drugs among physicians, dentists, and nurses.

methodsUsing questionnaires, the current knowledge of MRONJ was assessed among dentists, physicians, and nurses, who were divided into group I, which included specialties that directly assist cancer patients, and group II, which included other specialties. The questionnaires assessed the characteristics of the health professionals, training time, and specialties; their knowledge of AR and AA drugs; and their knowledge of MRONJ.

resultsA total of 1370 health professionals participated in the study, including 1032 dentists, 239 physicians, and 99 nurses. Among dentists and physicians, the training time (p = 0.036 and p < 0.001, respectively) and specialization in group I domains (p < 0.001 and p < 0.001, respectively) had a significant impact on MRONJ knowledge, while nurses showed no significant impact regardless of the training time and specialty. Less than 10% of the physicians and dentists could correlate the signs and symptoms of all stages of MRONJ.

conclusionThe findings indicated a notable lack of knowledge regarding MRONJ among dental surgeons and physicians, and especially among nurses. More experienced professionals and specialists in the areas that assist cancer patients usually have a greater understanding of the dentist's role in MRONJ prevention, diagnosis, treatment, and patient care and will introduce or are already using AR and AA drugs.

Indexed as

KnowledgeAdultBisphosphonate-Associated Osteonecrosis of the JawBone Density Conservation AgentsBrazilCross-Sectional StudiesDentistsDiagnosis, DifferentialFemaleHealth Knowledge, Attitudes, PracticeHealth PersonnelHumansMaleMiddle AgedNursesPhysiciansBone Density Conservation AgentsBisphosphonate-related osteonecrosis of the jawHealth professionalsMedication-related osteonecrosis of the jawOsteonecrosis of the jawQuestionnaires

Identifiers

PMID32144584
OpenAlexW3010606386

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.