Evidence map›Paper›PMID 32144519›Full record

ReviewAnnals of intensive care2020

Prescription of CRRT: a pathway to optimize therapy.

Ayman Karkar, Claudio Ronco

3 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Annals of intensive care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 89 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed, 7 pooled it
15.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04751838 unknown statusnot on this map

Development and Validation of a Simple-to-use Nomogram for Predicting In-hospital Mortality in Acute Heart Failure Patients Undergoing Continuous Renal Replacement Therapy

TypeobservationalSponsorQilu Hospital of Shandong UniversityRan2020 to 2021Enrolled226ConditionsHeart Failure AcuteArmsno intervention
NCT05638711 completednot on this map

Built-in Calculator Optimizes Continuous Veno-venous Hemofiltration Prescription and Improves Therapeutic Quality in Critically-ill Acute Kidney Injury Patients

TypeobservationalSponsorTaipei Medical UniversityRan2019 to 2022Enrolled1ConditionsCVVH, Filtration Fraction, Built-in CulculatorArmsBuilt-in calculator to calculate Filtration fraction
NCT06901011 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Continuous Renal Replacement Therapy Doses in Critically Ill Patients With Acute Kidney Injury

TypeinterventionalSponsorFundacion Clinic per a la Recerca BiomédicaRan2025 to 2027Enrolled100ConditionsRenal Replacement Therapy for Acute Kidney Injury in ICU, Continuous Renal Replacement Therapy (CRRT)Armscontinuous renal replacement therapy
3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 7 syntheses or guidelines pooled it, 197 citations in OpenAlex.

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29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Ayman KarkarMedical Affairs-Renal Care, Scientific Office, Baxter A.G., Burj Al Salam, PO Box 64332, Dubai, United Arab Emirates. ayman_karkar@baxter.com.ORCID http://orcid.org/0000-0002-7343-1296
Claudio RoncoMedical Affairs-Renal Care, Scientific Office, Baxter A.G., Burj Al Salam, PO Box 64332, Dubai, United Arab Emirates.
Baxter (United States) · USInternational Renal Research Institute of Vicenza · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute kidney injury (AKI), especially when caused or accompanied by sepsis, is associated with prolonged hospitalization, progression to chronic kidney disease (CKD), financial burden, and high mortality rate. Continuous renal replacement therapy (CRRT) is a predominant form of renal replacement therapy (RRT) in the intensive care unit (ICU) due to its accurate volume control, steady acid-base and electrolyte correction, and achievement of hemodynamic stability. This manuscript reviews the different aspects of CRRT prescription in critically ill patients with severe AKI, sepsis, and multiorgan failure in ICU. These include the choice of CRRT versus Intermittent and extended hemodialysis (HD), life of the filter/dialyzer including assessment of filtration fraction, anticoagulation including regional citrate anticoagulation (RCA), prescribed versus delivered CRRT dose, vascular access management, timing of initiation and termination of CRRT, and prescription in AKI/sepsis including adsorptive methods of removing endotoxins and cytokines.

Indexed as

Acute kidney injuryAdsorptionAnticoagulationContinuous renal replacement therapyoXirisSepsisVascular access

Identifiers

PMID32144519
PMCPMC7060300
OpenAlexW3010084248

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.