Evidence map›Paper›PMID 32144514›Full record

ArticleAnnals of intensive care2020

Optimal mean airway pressure during high-frequency oscillatory ventilation in an experimental model of acute respiratory distress syndrome: EIT-based method.

Songqiao Liu, Zhanqi Zhao, Li Tan, Lihui Wang, Knut Möller, Inéz Frerichs, Tao Yu, Yingzi Huang, Chun Pan, Yi Yang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Annals of intensive care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Observational
  2. Review
  3. Article
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  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Songqiao LiuDepartment of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Jiangsu Province, Nanjing, 210009, China.ORCID http://orcid.org/0000-0002-1875-1131
Zhanqi ZhaoInstitute of Technical Medicine, Furtwangen University, Jakob-Kienzle Strasse 17, 78054, VS-Schwenningen, Germany.
Li TanDepartment of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Jiangsu Province, Nanjing, 210009, China.
Lihui WangDepartment of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Jiangsu Province, Nanjing, 210009, China.
Knut MöllerInstitute of Technical Medicine, Furtwangen University, Jakob-Kienzle Strasse 17, 78054, VS-Schwenningen, Germany.
Inéz FrerichsDepartment of Anesthesiology and Intensive Care Medicine, University Medical Center of Schleswig-Holstein Campus Kiel, Arnold-Heller-Strasse 3, 24105, Kiel, Germany.
Tao YuDepartment of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Jiangsu Province, Nanjing, 210009, China.
Yingzi HuangDepartment of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Jiangsu Province, Nanjing, 210009, China.
Chun PanDepartment of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Jiangsu Province, Nanjing, 210009, China.
Yi YangDepartment of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Jiangsu Province, Nanjing, 210009, China.
Haibo QiuDepartment of Critical Care Medicine, Zhongda Hospital, School of Medicine, Southeast University, Jiangsu Province, Nanjing, 210009, China. haiboq2000@163.com.
Zhongda Hospital Southeast University · CNFurtwangen University · DEBeijing Tongren Hospital · CN

Funding

Jiangsu Province's Key Discipline / Laboratory of Medicine ZDXKA2016025Jiangsu Province's Key Provincial Talents Program ZDRCA2016082National Natural Science Foundation of China 81370180Natural Science Foundation of Jiangsu Province H201432
6 · The paper itself

Abstract

backgroundHigh-frequency oscillatory ventilation (HFOV) may theoretically provide lung protective ventilation. The negative clinical results may be due to inadequate mean airway pressure (mPaw) settings in HFOV. Our objective was to evaluate the air distribution, ventilatory and hemodynamic effects of individual mPaw titration during HFOV in ARDS animal based on oxygenation and electrical impedance tomography (EIT).

methodsARDS was introduced with repeated bronchoalveolar lavage followed by injurious mechanical ventilation in ten healthy male pigs (51.2 ± 1.9 kg). Settings of HFOV were 9 Hz (respiratory frequency), 33% (inspiratory time) and 70 cmH

resultsPaO

conclusionOur data suggested personalized optimal mPaw titration by EIT-based indices improves regional ventilation distribution and lung homogeneity during high-frequency oscillatory ventilation.

Indexed as

Acute respiratory distress syndromeElectrical impedance tomographyHigh-frequency oscillatory ventilationMean airway pressureTitration

Identifiers

PMID32144514
PMCPMC7060304
OpenAlexW3011106036

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.