Evidence map›Paper›PMID 32144496›Full record

ArticleBrain structure & function2020

CBPtools: a Python package for regional connectivity-based parcellation.

Niels Reuter, Sarah Genon, Shahrzad Kharabian Masouleh, Felix Hoffstaedter, Xiaojin Liu, Tobias Kalenscher, Simon B Eickhoff, Kaustubh R Patil

Abstract read
In one paragraph

Article in Brain structure & function, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Niels ReuterInstitute of Systems Neuroscience, Heinrich-Heine University, Düsseldorf, Germany.ORCID http://orcid.org/0000-0001-6895-3527
Sarah GenonInstitute of Systems Neuroscience, Heinrich-Heine University, Düsseldorf, Germany.ORCID http://orcid.org/0000-0002-7087-7882
Shahrzad Kharabian MasoulehInstitute of Systems Neuroscience, Heinrich-Heine University, Düsseldorf, Germany.ORCID http://orcid.org/0000-0003-4810-9542
Felix HoffstaedterInstitute of Systems Neuroscience, Heinrich-Heine University, Düsseldorf, Germany.ORCID http://orcid.org/0000-0001-7163-3110
Xiaojin LiuInstitute of Systems Neuroscience, Heinrich-Heine University, Düsseldorf, Germany.ORCID http://orcid.org/0000-0002-0725-2943
Tobias KalenscherComparative Psychology, Institute of Experimental Psychology, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany.ORCID http://orcid.org/0000-0002-0358-9020
Simon B EickhoffInstitute of Systems Neuroscience, Heinrich-Heine University, Düsseldorf, Germany.ORCID http://orcid.org/0000-0001-6363-2759
Kaustubh R PatilInstitute of Systems Neuroscience, Heinrich-Heine University, Düsseldorf, Germany. k.patil@fz-juelich.de.ORCID http://orcid.org/0000-0002-0289-5480

Funding

Deutsche Forschungsgemeinschaft GE 2835/1-1Horizon 2020 7202070Horizon 2020 785907
6 · The paper itself

Abstract

Regional connectivity-based parcellation (rCBP) is a widely used procedure for investigating the structural and functional differentiation within a region of interest (ROI) based on its long-range connectivity. No standardized software or guidelines currently exist for applying rCBP, making the method only accessible to those who develop their own tools. As such, there exists a discrepancy between the laboratories applying the procedure each with their own software solutions, making it difficult to compare and interpret the results. Here, we outline an rCBP procedure accompanied by an open source software package called CBPtools. CBPtools is a Python (version 3.5+) package that allows users to run an extensively evaluated rCBP analysis workflow on a given ROI. It currently supports two modalities: resting-state functional connectivity and structural connectivity based on diffusion-weighted imaging, along with support for custom connectivity matrices. Analysis parameters are customizable and the workflow can be scaled to a large number of subjects using a parallel processing environment. Parcellation results with corresponding validity metrics are provided as textual and graphical output. Thus, CBPtools provides a simple plug-and-play, yet customizable way to conduct rCBP analyses. By providing an open-source software we hope to promote reproducible and comparable rCBP analyses and, importantly, make the rCBP procedure readily available. Here, we demonstrate the utility of CBPtools using a voluminous data set on an average compute-cluster infrastructure by performing rCBP on three ROIs prominently featured in parcellation literature.

Indexed as

Diffusion Magnetic Resonance ImagingMagnetic Resonance ImagingSoftwareAccess to InformationAdultBrainBrain MappingFemaleHumansImage Processing, Computer-AssistedMaleNeural PathwaysClusteringConnectivity-based parcellationDiffusion-weighted imagingResting stateSoftware

Identifiers

PMID32144496
PMCPMC7271019

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.