ArticleProceedings of the National Academy of Sciences of the United States of America2020
Central neurogenetic signatures of the visuomotor integration system.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 32 citations in OpenAlex.
- Impaired visual-motor integration function in children with attention-deficit/hyperactivity disorder: potential neural correlates from resting-state fNIRS.European child & adolescent psychiatry · 2026Article
- Multiomics reveal key inflammatory drivers of severe obesity: IL4R, LILRA5, and OSM.Cell genomics · 2025Article
- Spatiotemporal patterns of locus coeruleus integrity predict cortical tau and cognition.Nature aging · 2024Article
- Changes in effective connectivity during the visual-motor integration tasks: a preliminary f-NIRS study.Behavioral and brain functions : BBF · 2024Article
- Open datasets and code for multi-scale relations on structure, function and neuro-genetics in the human brain.Scientific data · 2024Article
- Lateralized Functional Connectivity of the Sensorimotor Cortex and its Variations During Complex Visuomotor Tasks.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Neurogenetics of Dynamic Connectivity Patterns Associated With Obsessive-Compulsive Symptoms in Healthy Children.Biological psychiatry global open science · 2022Article
- The role of educational attainment and brain morphology in major depressive disorder: Findings from the ENIGMA major depressive disorder consortium.Journal of psychopathology and clinical science · 2022Article
- Connectomic-genetic signatures in the cerebral small vessel disease.Neurobiology of disease · 2022Article
- Differential impact of movement on the alpha and gamma dynamics serving visual processing.Journal of neurophysiology · 2022Article
- A scoping review of electroencephalographic (EEG) markers for tracking neurophysiological changes and predicting outcomes in substance use disorder treatment.Frontiers in human neuroscience · 2022Article
- Neurogenetic traits outline vulnerability to cortical disruption in Parkinson's disease.NeuroImage. Clinical · 2022Article
- Transcriptional signatures of synaptic vesicle genes define myotonic dystrophy type I neurodegeneration.Neuropathology and applied neurobiology · 2021Article
- Divergent connectomic organization delineates genetic evolutionary traits in the human brain.Scientific reports · 2021Article
- Reliability of the Dynavision task in virtual reality to explore visuomotor phenotypes.Scientific reports · 2021Article
- Cortical Networks of Creative Ability Trace Gene Expression Profiles of Synaptic Plasticity in the Human Brain.Frontiers in human neuroscience · 2021Article
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Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
Abstract
Visuomotor impairments characterize numerous neurological disorders and neurogenetic syndromes, such as autism spectrum disorder (ASD) and Dravet, Fragile X, Prader-Willi, Turner, and Williams syndromes. Despite recent advances in systems neuroscience, the biological basis underlying visuomotor functional impairments associated with these clinical conditions is poorly understood. In this study, we used neuroimaging connectomic approaches to map the visuomotor integration (VMI) system in the human brain and investigated the topology approximation of the VMI network to the Allen Human Brain Atlas, a whole-brain transcriptome-wide atlas of cortical genetic expression. We found the genetic expression of four genes-TBR1, SCN1A, MAGEL2, and CACNB4-to be prominently associated with visuomotor integrators in the human cortex. TBR1 gene transcripts, an ASD gene whose expression is related to neural development of the cortex and the hippocampus, showed a central spatial allocation within the VMI system. Our findings delineate gene expression traits underlying the VMI system in the human cortex, where specific genes, such as TBR1, are likely to play a central role in its neuronal organization, as well as on specific phenotypes of neurogenetic syndromes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.