Evidence map›Paper›PMID 32143688›Full record

ArticleBMC research notes2020

Exploratory analysis of myocardial function after extracorporeal cardiopulmonary resuscitation vs conventional cardiopulmonary resuscitation.

Joseph E Tonna, Stephen H McKellar, Craig H Selzman, Stavros Drakos, Antigone G Koliopoulou, Iosif Taleb, Gregory J Stoddard, Josef Stehlik, Frederick G P Welt, James F Fair and 2 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in BMC research notes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Joseph E TonnaDivision of Emergency Medicine, University of Utah School of Medicine, 30 N 1900 E, Salt Lake City, UT, 84132, USA. joseph.tonna@hsc.utah.edu.ORCID http://orcid.org/0000-0001-8879-2628
Stephen H McKellarDivision of Cardiothoracic Surgery, University of Utah School of Medicine, 30 N 1900 E, 3C127, Salt Lake City, UT, 84132, USA.
Craig H SelzmanDivision of Cardiothoracic Surgery, University of Utah School of Medicine, 30 N 1900 E, 3C127, Salt Lake City, UT, 84132, USA.
Stavros DrakosDivision of Cardiology, University of Utah School of Medicine, Salt Lake City, USA.
Antigone G KoliopoulouDivision of Cardiothoracic Surgery, University of Utah School of Medicine, 30 N 1900 E, 3C127, Salt Lake City, UT, 84132, USA.
Iosif TalebDivision of Cardiology, University of Utah School of Medicine, Salt Lake City, USA.
Gregory J StoddardDivision of Epidemiology, University of Utah School of Medicine, Salt Lake City, USA.
Josef StehlikDivision of Cardiology, University of Utah School of Medicine, Salt Lake City, USA.
Frederick G P WeltDivision of Cardiology, University of Utah School of Medicine, Salt Lake City, USA.
James F FairDivision of Emergency Medicine, University of Utah School of Medicine, 30 N 1900 E, Salt Lake City, UT, 84132, USA.
Kathleen StoddardCardiovascular ICU, University of Utah, Salt Lake City, USA.
Scott T YoungquistDivision of Emergency Medicine, University of Utah School of Medicine, 30 N 1900 E, Salt Lake City, UT, 84132, USA.
University of Utah · US

Funding

Utah Center for Clinical and Translational ScienceUL1TR002538 · NCATS · UNIVERSITY OF UTAH · PI HESS, RACHEL, MAJERSIK, JENNIFER JUHL · 2018 to 2022
$26.0M
Optimizing Selection and Management of Cardiac Arrest Patients Treated with ECMOK23HL141596 · NHLBI · UNIVERSITY OF UTAH · PI TONNA, JOSEPH EDWARD · 2018 to 2022
$945k
NCATS NIH HHS UL1 TR002538NCATS NIH HHS UL1TR002538NHLBI NIH HHS K23 HL141596NHLBI NIH HHS K23HL141596
6 · The paper itself

Abstract

objectiveVentricular unloading is associated with myocardial recovery. We sought to evaluate the association of extracorporeal cardiopulmonary resuscitation (ECPR) on myocardial function after cardiac arrest. We conducted a retrospective exploratory analysis, comparing ejection fraction (EF) after adult cardiac arrest, between ECPR and conventional CPR.

resultsAmong 1119 cases of cardiac arrest, 116 had an echocardiogram post-return of spontaneous circulation (ROSC) and were included. Thirty-eight patients had ≥ 2 echocardiograms. ECPR patients had differences in age, hypertension and chronic heart failure. ECPR patients had a lower EF post-ROSC (24% vs 45%; p < 0.01) and were more likely to undergo percutaneous coronary intervention (25% vs 3%; p < 0.01). In multivariate analysis, only ECPR use (β-coeff: 10.4 [95% CI 3.68-17.13]; p < 0.01) independently predicted improved myocardial function. In this exploratory study, EF after cardiac arrest may be more likely to improve among ECPR patients than CCPR patients. Our methodology should be replicated to confirm or refute the validity of our findings.

Indexed as

AdultAgedCardiopulmonary ResuscitationEchocardiographyFemaleHumansHypertensionMaleMiddle AgedMultivariate AnalysisOut-of-Hospital Cardiac ArrestPercutaneous Coronary InterventionRecovery of FunctionRetrospective StudiesCardiac arrestCardiac functionExtracorporeal cardiopulmonary resuscitation (ECPR)Myocardial recoveryVentricular unloading

Identifiers

PMID32143688
PMCPMC7060522
OpenAlexW3011798798

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.