Evidence map›Paper›PMID 32143661›Full record

Observational studyScandinavian journal of trauma, resuscitation and emergency medicine2020

The volume-outcome relationship among severely injured patients admitted to English major trauma centres: a registry study.

Charlie A Sewalt, Eveline J A Wiegers, Fiona E Lecky, Dennis den Hartog, Stephanie C E Schuit, Esmee Venema, Hester F Lingsma

Abstract readObservational Study
In one paragraph

Observational study in Scandinavian journal of trauma, resuscitation and emergency medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Transport and destination hospital for patients with suspected multiple and/or severe injuries - a systematic review and clinical practice guideline update.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Pooled it
  2. Article
  3. Observational
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Charlie A SewaltDepartment of Public Health, Erasmus MC University Medical Centre, P.O. Box 2040, 3000, CA, Rotterdam, The Netherlands. c.sewalt@erasmusmc.nl.ORCID http://orcid.org/0000-0003-3270-4814
Eveline J A WiegersDepartment of Public Health, Erasmus MC University Medical Centre, P.O. Box 2040, 3000, CA, Rotterdam, The Netherlands.
Fiona E LeckySchool of Health and Related Research, Sheffield University. Salford Royal NHS Foundation Trust, Salford, UK.
Dennis den HartogTrauma Research Unit, Department of Surgery, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands.
Stephanie C E SchuitDepartment of Emergency Medicine, Erasmus MC University Medical Centre, Rotterdam, The Netherlands.
Esmee VenemaDepartment of Public Health, Erasmus MC University Medical Centre, P.O. Box 2040, 3000, CA, Rotterdam, The Netherlands.
Hester F LingsmaDepartment of Public Health, Erasmus MC University Medical Centre, P.O. Box 2040, 3000, CA, Rotterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMany countries have centralized and dedicated trauma centres with high volumes of trauma patients. However, the volume-outcome relationship in severely injured patients (Injury Severity Score (ISS) > 15) remains unclear. The aim of this study was to determine the association between hospital volume and outcomes in Major Trauma Centres (MTCs).

methodsA retrospective observational cohort study was conducted using the Trauma Audit and Research Network (TARN) consisting of all English Major Trauma Centres (MTCs). Severely injured patients (ISS > 15) admitted to a MTC between 2013 and 2016 were included. The effect of hospital volume on outcome was analysed with random effects logistic regression models with a random intercept for centre and was tested for nonlinearity. Primary outcome was in-hospital mortality.

resultsA total of 47,157 severely injured patients from 28 MTCs were included in this study. Hospital volume varied from 69 to 781 severely injured patients per year. There were small between-centre differences in mortality after adjusting for important demographic and injury severity characteristics (adjusted 95% odds ratio range: 0.99-1.01). Hospital volume was found to be linear and not associated with in-hospital mortality (adjusted odds ratio (aOR) 1.02 per 10 patients, 95% confidence interval (CI) 0.68-1.54, p = 0.92).

conclusionsDespite the large variation in volume of the included MTCs, no relationship between hospital volume and outcome of severely injured patients was found. These results suggest that centres with similar structure and processes of care can achieve comparable outcomes in severely injured patients despite the number of severely injured patients they treat.

Indexed as

AdultAgedEnglandFemaleHospitalizationHospital MortalityHumansInjury Severity ScoreLogistic ModelsMaleMiddle AgedOdds RatioRegistriesRetrospective StudiesTime-to-TreatmentTrauma CentersQuality of trauma careSeverely injuryVolume-outcome relationship

Identifiers

PMID32143661
PMCPMC7059707

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.