SynthesisBMC musculoskeletal disorders2020
Higher risk of revision in total knee arthroplasty after high tibial osteotomy: a systematic review and updated meta-analysis.
Synthesis in BMC musculoskeletal disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Comparative outcomes of revision total knee arthroplasty: a systematic review and meta-Analysis of high tibial osteotomy vs. unicompartmental knee arthroplasty.BMC musculoskeletal disorders · 2025Pooled it
- Surgical interventions for symptomatic knee osteoarthritis: a network meta-analysis of randomized control trials.BMC musculoskeletal disorders · 2023Pooled it
- Clinical Outcomes of Revision Total Knee Arthroplasty after High Tibial Osteotomy and Unicompartmental Knee Arthroplasty: A Systematic Review and Meta-Analysis.Orthopaedic surgery · 2022Pooled it
- Prior osteosynthesis-unlike osteotomy-raises revision risk after total knee arthroplasty, predominantly via periprosthetic infection.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Article
- A long-term comparison of radiographic and clinical outcomes between 62% and 70% weight-bearing line targets in medial opening wedge high tibial osteotomy.Journal of experimental orthopaedics · 2026Article
- Short-term benefits of image-based robotic assistance in TKA after prior HTO: A comparative study.Journal of experimental orthopaedics · 2026Article
- Complications and Reoperation Rates of Total Knee Arthroplasty After High Tibial Osteotomy: A Matched Cohort Analysis From a Nationwide Database.Arthroplasty today · 2026Article
- Article
- Decreasing utilization of tibial osteotomy and regional disparities: A population-based study of all surgeries in Sweden from 2008 to 2023.Journal of experimental orthopaedics · 2025Article
- Cost-effectiveness of total knee arthroplasty, unicompartmental knee arthroplasty, and high tibial osteotomy for medial compartment knee osteoarthritis in young patients: a Canadian public payer perspective.Journal of orthopaedic surgery and research · 2025Article
- Total knee arthroplasty following lateral closing-wedge high tibial osteotomy versus primary total knee arthroplasty: a propensity score matching study.Journal of orthopaedic surgery and research · 2024Article
- Article
- Total knee arthroplasty post-high tibial osteotomy, results of an early experience from a North African arthroplasty unit, and a comprehensive review of the literature.Journal of orthopaedic surgery and research · 2023Review
- Double level osteotomy for medial osteoarthritis and bifocal varus malalignment has excellent short-term results while maintaining physiologic radiographic joint parameters.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Observational
- After-hour elective total knee arthroplasty does not affect clinical outcomes but negatively affects alignment.Archives of orthopaedic and trauma surgery · 2023Article
- Higher survival rate in total knee arthroplasty after high tibial osteotomy than that after unicompartmental knee arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
- Medial unicompartmental knee replacement is a viable treatment option after failed high tibial osteotomy: a systematic review.EFORT open reviews · 2022Review
- Considerations of the Posterior Tibial Slope in Anterior Cruciate Ligament Reconstruction: a Scoping Review.Current reviews in musculoskeletal medicine · 2022Article
- Chinese Clinical Practice Guidelines in Treating Knee Osteoarthritis by Periarticular Knee Osteotomy.Orthopaedic surgery · 2022Article
- [Are the results of total knee arthroplasty after high tibial osteotomy worse?]Der Orthopade · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundHigh tibial osteotomy is commonly performed in young patients with high activity demand. Several studies have reported outcome of HTO. The reported 10-year survival ranged from 79 to 97.6%. The reported 15-year survival ranged from 56 to 65.5%, resulting in the need for conversion to TKA. Primary TKA now provides satisfactory long-term outcome in terms of function and survival. Researches have been conducted to compare clinical outcome between primary TKA and TKA after HTO to see if TKA should be the prior treatment rather than HTO in some cases. But the results were inconsistent. This study aims to compare the risk of revision and other parameters between total knee arthroplasty after high tibial osteotomy and primary total knee arthroplasty.
methodsSearches and screens of the relevant literature were conducted, after which data were extracted and pooled analysis was performed to compare the clinical outcomes between the two groups.
resultsA total of 14 studies with 144,692 cases were included. Pooled analysis showed significantly more revisions and complications, and more tibial component loosening and impingement in postoperative X-ray in the HTO-TKA group. Surgical complexity during conversion to total knee arthroplasty was summarised and listed in table.
conclusionHigh tibial osteotomy offers satisfactory pain relief and functional outcome in selected patients with high activity demand. However, the need for subsequent TKA should be noted, which might be a technically challenging procedure with significantly higher risk of revision comparing to primary TKA.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.