ArticleBMC plant biology2020
Unique miRNAs and their targets in tomato leaf responding to combined drought and heat stress.
Article in BMC plant biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 73 citations in OpenAlex.
- Article
- Genome-wide analysis of conserved and novel miRNAs in mango mesocarp reveals early regulatory networks involved in postharvest heat stress response.Scientific reports · 2026Article
- Integrative Transcriptomic and Evolutionary Analysis of Drought and Heat Stress Responses inPlants (Basel, Switzerland) · 2025Article
- Function of floral fragrance-related microRNAs and their targets in Hedychium coronarium.BMC genomics · 2025Article
- Mechanisms of plant acclimation to multiple abiotic stresses.Communications biology · 2025Review
- Article
- Role of transcriptional regulation in auxin-mediated response to abiotic stresses.Frontiers in genetics · 2024Review
- Study of the genetic variability of durum wheat (AoB PLANTS · 2024Article
- Review
- Review
- Dynamic Regulation of Grapevine's microRNAs in Response to Mycorrhizal Symbiosis and High Temperature.Plants (Basel, Switzerland) · 2023Article
- Coordinating Diverse Functions of miRNA and lncRNA in Fleshy Fruit.Plants (Basel, Switzerland) · 2023Review
- Metabolic pathways engineering for drought or/and heat tolerance in cereals.Frontiers in plant science · 2023Review
- Development and verification of SSR markers from drought stress-responsive miRNAs in Dongxiang wild rice (Oryza rufipogon Griff.).Functional & integrative genomics · 2022Article
- Characterization and bioinformatics analysis ofNon-coding RNA research · 2022Article
- Molecular Aspects of MicroRNAs and Phytohormonal Signaling in Response to Drought Stress: A Review.Current issues in molecular biology · 2022Review
- Molecular insights into sensing, regulation and improving of heat tolerance in plants.Plant cell reports · 2022Review
- 'Omics' approaches in developing combined drought and heat tolerance in food crops.Plant cell reports · 2022Review
- Drought tolerance improvement in3 Biotech · 2022Review
- Down-Regulation of Cytokinin Receptor GenePlants (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundBoth drought and heat stress are serious global problems, leading to agricultural production loss. MicroRNAs (miRNAs) play important roles in plant species responding to individual drought and heat stress. However, the miRNAs and mRNAs in association with combined drought and heat in crops like tomato remains unclear.
resultsWe studied the crosstalk of miRNAs and their target genes in tomato plants grown under simultaneous drought and heat stress that frequently happen in field conditions. In total, 335 known miRNAs representing 55 miRNA families and 430 potential novel miRNAs were identified in Solanum lycopersicum L. using small RNA deep sequencing. Through expression analysis, miRNAs in association with drought, heat and the combination of these were investigated. In total, 61, 74 and 37 miRNAs were differentially regulated for combination (of both stresses) vs control, combination vs drought and combination vs heat, respectively. Target genes with different expression levels were found using degradome sequencing, which were mainly involved in transcription factor activity, sequence-specific DNA binding, transcription, regulation of transcription, nucleus, DNA binding etc. The quantitative real-time polymerase chain reaction (qRT-PCR) results confirmed the accuracy of sequencing.
conclusionsOur study serves as valuable knowledge on how crop adapted to combined drought and heat stress by regulating miRNAs and mRNAs, which provide information for crop improvement to deal with future climate changes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.