ArticleBMC microbiology2020
Identification and functional characterization of NbMLP28, a novel MLP-like protein 28 enhancing Potato virus Y resistance in Nicotiana benthamiana.
Article in BMC microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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24 citing papers in PubMed, 40 citations in OpenAlex.
- Unravelling the molecular mechanisms of vegetative-to-reproductive transition in Cynara cardunculus by RNA-Seq analysis.Plant molecular biology · 2026Article
- Characterization of the major latex protein gene family and functional analysis ofFrontiers in plant science · 2026Article
- Overexpression of a major latex-like protein from wild Arachis (AdMLP11) confers tolerance to recurrent drought stress.Genetics and molecular biology · 2026Article
- Genome-wide analysis of soybean MLPs reveals evolutionary and structural insights into drought, salt stress and ABA responses.BMC plant biology · 2025Article
- A Major Latex Protein-Encoding Gene fromInternational journal of molecular sciences · 2025Article
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- Identification of two QTLs for web blotch resistance in peanut (Arachis hypogaea L.) based on BSA-seq.BMC plant biology · 2024Article
- Genome-Wide Characterization and Expression Analyses of Major Latex Protein Gene Family inInternational journal of molecular sciences · 2024Article
- Genome-wide identification of rubber tree pathogenesis-related 10 (PR-10) proteins with biological relevance to plant defense.Scientific reports · 2024Article
- Construction of Host Plant Insect-Resistance Mutant Library by High-Throughput CRISPR/Cas9 System and Identification of A Broad-Spectrum Insect Resistance Gene.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Identification and analysis of major latex protein (Frontiers in plant science · 2024Article
- Nanoplatforms for the Delivery of Nucleic Acids into Plant Cells.International journal of molecular sciences · 2023Review
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- Comprehensive Analysis of Major Latex-Like Protein Family Genes in Cucumber (International journal of molecular sciences · 2023Article
- Set up from the beginning: The origin and early development of cassava storage roots.Plant, cell & environment · 2022Article
- Serratia marcescens-S3 inhibits Potato virus Y by activating ubiquitination of molecular chaperone proteins NbHsc70-2 in Nicotiana benthamiana.Microbial biotechnology · 2022Article
- Transcriptomic Reprogramming, Alternative Splicing and RNA Methylation in Potato (Plants (Basel, Switzerland) · 2022Article
- HACC-Based Nanoscale Delivery of the NbMLP28 Plasmid as a Crop Protection Strategy for Viral Diseases.ACS omega · 2021Article
- Symbiotic responses of Lotus japonicus to two isogenic lines of a mycorrhizal fungus differing in the presence/absence of an endobacterium.The Plant journal : for cell and molecular biology · 2021Article
- Article
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Authors and funding
15 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundMajor latex proteins (MLPs) belong to the MLP subfamily in Bet v 1 protein family and respond to both biotic and abiotic stresses, which play critical roles in plant disease resistance. As the type species of widely distributed and economically devastating Potyvirus, Potato virus Y (PVY) is one of the major constraints to important crop plants including tobacco (Nicotiana benthamiana) worldwide. Despite the great losses owing to PVY infection in tobacco, there is no previous study investigating the potential role of MLPs in developing resistance to viral infection.
resultsIn this study, for the first time we have identified and functionally analyzed the MLP-like protein 28 from N. benthamiana, denoted as NbMLP28 and investigated its role in conferring resistance to N. benthamiana against PVY infection. NbMLP28 was localized to the plasmalemma and nucleus, with the highest level in the root. NbMLP28 gene was hypothesized to be triggered by PVY infection and was highly expressed in jasmonic acid (JA) signaling pathway. Further validation was achieved through silencing of NbMLP28 through virus-induced gene silencing (VIGS) that rendered N. benthamiana plants more vulnerable to PVY infection, contrary to overexpression that enhanced resistance.
conclusionsTaken together, this is the first study describing the role of NbMLP28 in tobacco against PVY infection and provide a pivotal point towards obtaining pathogen-resistant tobacco varieties through constructing new candidate genes of MLP subfamily.
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