ArticleBiomedicines2020
Outer Nuclear Layer Damage for Detection of Early Retinal Toxicity of Hydroxychloroquine.
Article in Biomedicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 14 citations in OpenAlex.
- Optical Coherence Tomography and Angiography in Hydroxychloroquine Retinopathy: A Narrative Review.Diagnostics (Basel, Switzerland) · 2026Review
- Optical coherence tomography angiography parameters in patients on hydroxychloroquine therapy.International ophthalmology · 2026Article
- Association between hydroxychloroquine intake and damage to the outer nuclear layer in eyes without manifest retinal toxicity.BMC ophthalmology · 2024Article
- Review of Retinal Imaging Modalities for Hydroxychloroquine Retinopathy.Diagnostics (Basel, Switzerland) · 2023Review
- Analysis of the outer retinal thickness pixel maps for the screening of hydroxychloroquine retinopathy.International ophthalmology · 2023Article
- A Case of Tacrolimus Maculopathy.Clinics and practice · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In hydroxychloroquine (HCQ) retinopathy, early detection of asymptomatic retinal changes and the interruption of the drug are essential to prevent permanent vision loss. Our purpose was to investigate the roles of ganglion cell layer (GCL) and outer nuclear layer (ONL) thicknesses measured by optical coherence tomography (OCT) in the early diagnosis of retinopathy. One hundred and fourteen eyes of 76 individuals with HCQ treatment were enrolled in the study (42 eyes with impaired visual field (VF) and 72 eyes with nondamaged VF). We found that ONL was significantly decreased in the HCQ retinopathy group compared with the control group in the nasal macula (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.