Trial reportBiomolecules2020
An Oral Rinse Active Matrix Metalloproteinase-8 Point-of-Care Immunotest May Be Less Accurate in Patients with Crohn's Disease.
Trial report in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 25 citations in OpenAlex.
- Prevalence of Periodontitis and Tooth Loss Among Older Adult Women With Low Bone Mineral Density: Protocol for a Cross-Sectional Study.JMIR research protocols · 2026Article
- Diagnostic Accuracy of Salivary Periodontal Biomarkers Is Reduced in Patients With Crohn's Disease.Clinical and experimental dental research · 2026Article
- Research advances in early diagnosis and treatment strategies for peri-implantitis: from microecology to regenerative therapy.Frontiers in cellular and infection microbiology · 2026Review
- Point-of-Care Biomarker Monitoring of Treatment Efficacy: Changes in Mouthrinse Active Matrix Metalloproteinase-8 (aMMP-8) Concentrations Following Periodontal Anti-Infective Treatment.International journal of dentistry · 2026Article
- Cytokine Changes in Gingival Crevicular Fluid and Serum After Non-Surgical Periodontal Therapy in Patients with Periodontitis: A Systematic Review and Narrative Synthesis.Journal of clinical medicine · 2025Review
- Salivary trimethylamine N-oxide: a novel non-invasive marker for periodontal inflammation.Clinical oral investigations · 2025Article
- Salivary Th17 cytokine, human β-defensin 1-3, and salivary scavenger and agglutinin levels in Crohn's disease.Clinical oral investigations · 2024Article
- Correlations between different protein species of oral rinse MMP-8 and patient-related factors.Clinical and experimental dental research · 2023Article
- Oral findings in patients with cartilage-hair hypoplasia - cross-sectional observational study.Orphanet journal of rare diseases · 2023Observational
- A Comparative Analysis of Treatment-Related Changes in the Diagnostic Biomarker Active Metalloproteinase-8 Levels in Patients with Periodontitis.Diagnostics (Basel, Switzerland) · 2023Article
- Salivary IgA and IgG Antibody Responses against Periodontitis-Associated Bacteria in Crohn's Disease.International journal of molecular sciences · 2023Article
- Determination of the Accuracy of Salivary Biomarkers for Periodontal Diagnosis.Diagnostics (Basel, Switzerland) · 2022Article
- Diagnostic Accuracy of Salivary aMMP-8 Test in Infertile Women and Blood Finding Analysis.Acta stomatologica Croatica · 2022Article
- Insights Into the Role of Matrix Metalloproteinases in Cancer and its Various Therapeutic Aspects: A Review.Frontiers in molecular biosciences · 2022Review
- Active matrix metalloproteinase-8 (aMMP-8) point-of-care test (POCT) in the COVID-19 pandemic.Expert review of proteomics · 2021Review
- An aMMP-8 Point-of-Care and Questionnaire Based Real-Time Diagnostic Toolkit for Medical Practitioners.Diagnostics (Basel, Switzerland) · 2021Article
- Diagnostic Accuracy of Oral Fluids Biomarker Profile to Determine the Current and Future Status of Periodontal and Peri-Implant Diseases.Diagnostics (Basel, Switzerland) · 2020Review
- Matrix Metalloproteinases in Health and Disease.Biomolecules · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The diagnostic accuracy of point-of-care (PoC) applications may be compromised in individuals with additional inflammatory conditions. This cross-sectional study examined the performance of a commercial oral rinse active matrix metalloproteinase-8 (aMMP-8) PoC immunotest in individuals with (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.