Evidence map›Paper›PMID 32143340›Full record

ArticleInternational journal of environmental research and public health2020

Serum Ghrelin Levels in Saudi Obese Asthmatic School-Children-Correlation with Interleukin-4, Interleukin-5, and Interleukin-21.

Mohammed Saeed Al-Ayed, Khaled Sadeq Al-Shaibari, Dhafer Alshehri, Mohammed Jamaan Alzahrani, Iman Nasser, Hamdan Saad Alaamri, Wed Ahmad Alaseeri, Ahmed A Mahfouz, Saeed Ali Alsareii, Ahmed Morad Asaad and 5 more

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. The Role of Peptides in Asthma-Obesity Phenotype.International journal of molecular sciences · 2024
    Review
  2. Review
  3. Regulatory Peptides in Asthma.International journal of molecular sciences · 2021
    Review
  4. Article
  5. Ghrelin as an Anti-Sepsis Peptide: Review.Frontiers in immunology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 2 countries.

Mohammed Saeed Al-AyedDepartments of Pediatrics, College of Medicine, Najran University, Najran, Saudi Arabia.
Khaled Sadeq Al-ShaibariDepartments of Pediatrics, College of Medicine, Najran University, Najran, Saudi Arabia.
Dhafer AlshehriDepartments of Pediatrics, College of Medicine, Najran University, Najran, Saudi Arabia.
Mohammed Jamaan AlzahraniDepartments of Pediatrics, College of Medicine, Najran University, Najran, Saudi Arabia.
Iman NasserDepartments of Pediatrics, College of Medicine, Najran University, Najran, Saudi Arabia.
Hamdan Saad AlaamriMinistry of Defense, Armed Forces Medical Services, Najran, Saudi Arabia.
Wed Ahmad AlaseeriMinistry of Health, Najran, Saudi Arabia.
Ahmed A MahfouzDepartment of Family and Community Medicine, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Saeed Ali AlsareiiDepartment of Surgery, College of Medicine, Najran University, Najran, Saudi Arabia.
Ahmed Morad AsaadDepartment of Microbiology, Zagazig University, Zagazig, Egypt.
Aamir MagzoubDepartment of Physiology, College of Medicine, Najran University, Najran, Saudi Arabia.
Mohammed Ansar QureshiDepartment of Microbiology, College of Medicine, Najran University, Najran, Saudi Arabia.
Ehab ElagabDepartment of Pathology, College of Medicine, Najran University, Najran, Saudi Arabia.
Elhashimi Eltayb HassanDepartment of Clinical Biochemistry, College of Applied Medical Sciences, Najran University, Najran, Saudi Arabia.
Mohammed Helmy Faris ShalayelUniversity of Hafr Al-Batin, Saudi Arabia.
Najran University · SAArmed Forces Hospital · SAKing Khalid University · SAMinistry of Health · SAUniversity of Hafr Al-Batin · SAZagazig University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ghrelin is a peptide hormone with direct or indirect effects on obesity and asthma. More data are required to understand the effect of ghrelin on the control and pathogenesis of these diseases. The aim of this study was to evaluate ghrelin levels in selected groups of children to identify the association between serum ghrelin, obesity, and the severity of asthma. The study included 401 school children selected from the Najran area and grouped into non-obese asthmatics, obese asthmatics, obese non-asthmatics and controls (non-obese non-asthmatics). Blood levels of ghrelin, interleukin (IL)-4, IL-5 and IL-21 were determined by ELISA. The mean ghrelin values were insignificantly increased in obese children compared with non-obese children. The highest blood ghrelin values were in the non-obese asthmatic group. Serum ghrelin, IL-4 and IL-21 levels were significantly increased in asthmatic children compared with non-asthmatic children (

Indexed as

AsthmaGhrelinInterleukinsChildHumansInflammationInterleukin-21Interleukin-4Interleukin-5ObesitySaudi ArabiaGhrelinInterleukin-21Interleukin-4Interleukin-5Interleukinsasthmaghrelininterleukin-21 (IL-21), obesityinterleukin-4 (IL-4)interleukin-5 (IL-5)

Identifiers

PMID32143340
PMCPMC7084446
OpenAlexW3010545324

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.