Evidence map›Paper›PMID 32143332›Full record

ArticleAnimals : an open access journal from MDPI2020

Characterization of Oligofructose-Induced Acute Rumen Lactic Acidosis and the Appearance of Laminitis in Zebu Cattle.

Rejane Dos Santos Sousa, Francisco Leonardo Costa de Oliveira, Mailson Rennan Borges Dias, Natalia Sato Minami, Leonardo do Amaral, Juliana Aparecida Alves Dos Santos, Raimundo Alves Barrêto Júnior, Antonio Humberto Hamad Minervino, Enrico Lippi Ortolani

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Subacute Ruminal Acidosis in Zebu Cattle: Clinical and Behavioral Aspects.Animals : an open access journal from MDPI · 2020
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Rejane Dos Santos SousaDepartment of Clinical Science, College of Veterinary Medicine and Animal Science, University of Sao Paulo (FMVZ/USP). Av. Prof. Orlando Marques de Paiva, 87, Cidade Universitária, São Paulo CEP 05508-270, SP, Brazil.
Francisco Leonardo Costa de OliveiraDepartment of Clinical Science, College of Veterinary Medicine and Animal Science, University of Sao Paulo (FMVZ/USP). Av. Prof. Orlando Marques de Paiva, 87, Cidade Universitária, São Paulo CEP 05508-270, SP, Brazil.
Mailson Rennan Borges DiasDepartment of Clinical Science, College of Veterinary Medicine and Animal Science, University of Sao Paulo (FMVZ/USP). Av. Prof. Orlando Marques de Paiva, 87, Cidade Universitária, São Paulo CEP 05508-270, SP, Brazil.ORCID 0000-0002-3201-391X
Natalia Sato MinamiDepartment of Clinical Science, College of Veterinary Medicine and Animal Science, University of Sao Paulo (FMVZ/USP). Av. Prof. Orlando Marques de Paiva, 87, Cidade Universitária, São Paulo CEP 05508-270, SP, Brazil.
Leonardo do AmaralDepartment of Clinical Science, College of Veterinary Medicine and Animal Science, University of Sao Paulo (FMVZ/USP). Av. Prof. Orlando Marques de Paiva, 87, Cidade Universitária, São Paulo CEP 05508-270, SP, Brazil.
Juliana Aparecida Alves Dos SantosDepartment of Clinical Science, College of Veterinary Medicine and Animal Science, University of Sao Paulo (FMVZ/USP). Av. Prof. Orlando Marques de Paiva, 87, Cidade Universitária, São Paulo CEP 05508-270, SP, Brazil.
Raimundo Alves Barrêto JúniorDepartment of Animal Science, Federal Rural University of the Semiarid Region (UFERSA). Av. Francisco Mota, s/nº-Bairro Pres. Costa e Silva, Mossoró CEP 59625-900, RN, Brazil.ORCID 0000-0002-9416-6129
Antonio Humberto Hamad MinervinoLaboratory of Animal Health (LARSANA), Federal University of Western Pará (UFOPA) Rua Vera Paz, s/n, Salé, Santarém CEP 68040-255, PA, Brazil.ORCID 0000-0002-6742-3652
Enrico Lippi OrtolaniDepartment of Clinical Science, College of Veterinary Medicine and Animal Science, University of Sao Paulo (FMVZ/USP). Av. Prof. Orlando Marques de Paiva, 87, Cidade Universitária, São Paulo CEP 05508-270, SP, Brazil.
Universidade de São Paulo · BRUniversidade Federal do Oeste do Pará · BRUniversidade Federal Rural do Semi-Árido · BR

Funding

Fundação de Amparo à Pesquisa do Estado de São Paulo 14/23547-8
6 · The paper itself

Abstract

The objective of this study was to characterize oligofructose-induced acute rumen lactic acidosis and its consequences in zebu cattle. We used 29 Nellore heifers which were submitted to experimental induction of laminitis by oligofructose excess. During the induction period, the animals underwent clinical examination, including laminitis diagnosis (hoof pressure testing and locomotion score) and blood and ruminal fluid sampling every six hours (over the initial 24 h) and every 12 h (up to 72 h), after the highest dose. Almost half of the animals (48.1%) required treatment with bicarbonate and saline to correct metabolic acidosis and dehydration. Due to this treatment, the animals were analyzed in treated (n = 13) and non-treated (n = 14) groups. The induction model promoted marked reduction in rumen pH, rumen anaerobiosis, carbon dioxide pressure, and increase in rumen lactate, blood osmolarity, and cortisol concentration. The animals treated had lower values of rumen pH and marked dehydration, evidenced by the increase in globular volume and serum urea. The clinical condition caused by excess oligofructose is severe, with the differential of the appearance of ephemeral fever and respiratory compensation against systemic acidosis, in addition to the frequent appearance of laminitis.

Indexed as

induction modelneloreruminal acidosissymptoms

Identifiers

PMID32143332
PMCPMC7143802
OpenAlexW3009671281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.