Evidence map›Paper›PMID 32143311›Full record

ArticleInternational journal of molecular sciences2020

Curcumin Attenuates Both Acute and Chronic Immune Nephritis.

Tianfu Wu, Bindiya Marakkath, Yujin Ye, Elhaum Khobahy, Mei Yan, Jack Hutcheson, Jiankun Zhu, Xinjin Zhou, Chandra Mohan

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Novel Insights into the Therapeutic Potential of Curcumin and Derivatives.International journal of molecular sciences · 2023
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Tianfu WuDepartment of Biomedical Engineering, University of Houston, Houston, TX 77204, USA.ORCID 0000-0003-4406-1449
Bindiya MarakkathDepartment of Biomedical Engineering, University of Houston, Houston, TX 77204, USA.
Yujin YeDepartment of Internal Medicine/Rheumatology, University of Texas, Southwestern Medical center, Dallas, TX 75390, USA.
Elhaum KhobahyDepartment of Internal Medicine/Rheumatology, University of Texas, Southwestern Medical center, Dallas, TX 75390, USA.
Mei YanDepartment of Internal Medicine/Rheumatology, University of Texas, Southwestern Medical center, Dallas, TX 75390, USA.
Jack HutchesonDepartment of Internal Medicine/Rheumatology, University of Texas, Southwestern Medical center, Dallas, TX 75390, USA.
Jiankun ZhuDepartment of Internal Medicine/Rheumatology, University of Texas, Southwestern Medical center, Dallas, TX 75390, USA.
Xinjin ZhouDepartment of Pathology, Baylor University Medical center at Dallas, Dallas, TX 75246, USA.
Chandra MohanDepartment of Biomedical Engineering, University of Houston, Houston, TX 77204, USA.
The University of Texas Southwestern Medical Center · USUniversity of Houston · USBaylor University Medical Center · US

Funding

AYURVEDIC ALTERNATIVES IN AUTOIMMUNITYR21AT004436 · NCCIH · UT SOUTHWESTERN MEDICAL CENTER · PI MOHAN, CHANDRA · 2009 to 2010
$430k
NIH HHS R21AT004436
6 · The paper itself

Abstract

Curcumin is known to have immunomodulatory potential in addition to anti-oxidant, anti-inflammatory and anti-carcinogenic effects. The aim of the present study is to investigate the therapeutic effects of curcumin on immune-mediated renal disease in an anti-glomerular basement membrane (GBM) model (representing acute kidney Injury, AKI) and murine lupus model (representing chronic kidney disease, CKD). In the AKI model, female anti-GBM 129/svj mice were administered with curcumin right before disease induction. In the CKD model, female MRL.

Indexed as

AnimalsAnti-Inflammatory AgentsAutoantibodiesAutoimmune DiseasesBasement MembraneCurcuminDisease Models, AnimalFemaleGlomerulonephritisKidneyKidney GlomerulusLupus NephritisMiceMice, Inbred MRL lprProteinuriaSignal TransductionAnti-Inflammatory AgentsAutoantibodiesCurcuminAnti-GBMcurcuminimmunomodulationlupus nephritismouse modelssignaling pathways

Identifiers

PMID32143311
PMCPMC7084772
OpenAlexW3010148106

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.