Evidence map›Paper›PMID 32143122›Full record

ReviewCurrent opinion in cell biology2020

Extensive GTPase crosstalk regulates Golgi trafficking and maturation.

Laura L Thomas, J Christopher Fromme

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in cell biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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  8. Sec7 regulatory domains scaffold autoinhibited and active conformations.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  9. Review
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  15. Role of theFrontiers in cell and developmental biology · 2022
    Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. The p24 Complex Contributes to Specify Arf1 for COPI Coat Selection.International journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Laura L ThomasDepartment of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA.
J Christopher FrommeDepartment of Molecular Biology and Genetics, Weill Institute for Cell and Molecular Biology, Cornell University, Ithaca, NY 14853, USA. Electronic address: jcf14@cornell.edu.
Cornell University · US

Funding

Regulation of Arf GTPase activation at the trans-Golgi networkR01GM098621 · NIGMS · CORNELL UNIVERSITY · PI FROMME, J CHRISTOPHER · 2012 to 2020
$2.9M
Regulation of Rab activation at the Golgi complexR01GM116942 · NIGMS · CORNELL UNIVERSITY · PI FROMME, J CHRISTOPHER · 2016 to 2019
$1.2M
NIGMS NIH HHS R01 GM098621NIGMS NIH HHS R01 GM116942
6 · The paper itself

Abstract

Virtually all transport events at the Golgi complex are regulated by Arf and Rab family GTPases. Recent work has advanced our knowledge regarding the mechanisms controlling GTPase activity, and it has become clear that GTPases do not act in isolation but rather function in complex networks of crosstalk and feedback. Together with earlier findings, these recent studies indicate that communication between GTPases, their regulatory proteins, effectors, and lipids plays a pivotal role in Golgi transport and cisternal maturation.

Indexed as

Cell MembraneGolgi ApparatusGTP PhosphohydrolasesHumansModels, BiologicalPhosphorylationProtein TransportGTP PhosphohydrolasesGolgiGTPaseSignalingTrafficking

Identifiers

PMID32143122
PMCPMC7483271
OpenAlexW3009145686

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.