ArticleeLife2020
Contextual and cross-modality modulation of auditory cortical processing through pulvinar mediated suppression.
Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
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Who cites it
57 citing papers in PubMed.
- Article
- Unraveling Audiovisual Perception Across Space and Time: A Neuroinspired Computational Architecture.The European journal of neuroscience · 2025Article
- Auditory cortex learns to discriminate audiovisual cues through selective multisensory enhancement.eLife · 2025Article
- Cross-modal enhancement of defensive behavior via parabigemino-collicular projections.Current biology : CB · 2024Article
- Thalamocortical architectures for flexible cognition and efficient learning.Trends in cognitive sciences · 2024Review
- Triple dissociation of visual, auditory and motor processing in mouse primary visual cortex.Nature neuroscience · 2024Article
- Live music stimulates the affective brain and emotionally entrains listeners in real time.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Sound suppresses earliest visual cortical processing after sight recovery in congenitally blind humans.Communications biology · 2024Article
- Neuroplastic changes in functional wiring in sensory cortices of the congenitally deaf: A network analysis.Human brain mapping · 2023Article
- Enhancement and contextual modulation of visuospatial processing by thalamocollicular projections from ventral lateral geniculate nucleus.Nature communications · 2023Article
- Dissection of neuronal circuits underlying sustained attention with the five-choice serial reaction time task.Neuroscience and biobehavioral reviews · 2023Review
- Article
- Article
- Spatial Distribution of Inhibitory Innervations of Excitatory Pyramidal Cells by Major Interneuron Subtypes in the Auditory Cortex.Bioengineering (Basel, Switzerland) · 2023Article
- Cortical-subcortical interactions in goal-directed behavior.Physiological reviews · 2023Review
- Implications of Neural Plasticity in Retinal Prosthesis.Investigative ophthalmology & visual science · 2022Article
- [Auditory response patterns of mouse primary auditory cortex to sound stimuli].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022Article
- Brain-wide mapping of inputs to the mouse lateral posterior (LP/Pulvinar) thalamus-anterior cingulate cortex network.The Journal of comparative neurology · 2022Article
- Review
- Striatal Injury Induces Overall Brain Alteration at the Pallial, Thalamic, and Cerebellar Levels.Biology · 2022Article
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Authors and funding
9 authors.
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Abstract
Lateral posterior nucleus (LP) of thalamus, the rodent homologue of primate pulvinar, projects extensively to sensory cortices. However, its functional role in sensory cortical processing remains largely unclear. Here, bidirectional activity modulations of LP or its projection to the primary auditory cortex (A1) in awake mice reveal that LP improves auditory processing in A1 supragranular-layer neurons by sharpening their receptive fields and frequency tuning, as well as increasing the signal-to-noise ratio (SNR). This is achieved through a subtractive-suppression mechanism, mediated largely by LP-to-A1 axons preferentially innervating specific inhibitory neurons in layer 1 and superficial layers. LP is strongly activated by specific sensory signals relayed from the superior colliculus (SC), contributing to the maintenance and enhancement of A1 processing in the presence of auditory background noise and threatening visual looming stimuli respectively. Thus, a multisensory bottom-up SC-pulvinar-A1 pathway plays a role in contextual and cross-modality modulation of auditory cortical processing.
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