ArticleAmerican journal of physiology. Heart and circulatory physiology2020
Neural control of blood pressure is altered following isolated leg heating in aged humans.
Article in American journal of physiology. Heart and circulatory physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis of heat-induced changes in cardiac function from over 400 laboratory-based heat exposure studies.Nature communications · 2025Pooled it
- Feasibility of unsupervised, home-based leg heat therapy in older adults: a pilot, sham-controlled trial.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Trial
- No effect of either heat therapy or aerobic exercise training on blood pressure in adults with untreated hypertension: a randomized clinical trial.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Trial
- Acute effects of leg heat therapy on walking performance and cardiovascular and inflammatory responses to exercise in patients with peripheral artery disease.Physiological reports · 2021Trial
- Heat Therapy: Targeting Health, Disease, and Disability.Comprehensive Physiology · 2026Review
- Systemic cardiovascular and carotid baroreflex support of arterial pressure during recovery from passive heat stress in young and older adults.Physiological reports · 2025Article
- Home-based heat therapy lowers blood pressure and improves endothelial function in older adults.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Article
- Improving glycemic control via heat therapy in older adults at risk for Alzheimer's disease (FIGHT-AD): a pilot study.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Article
- Effect of acute heat exposure on the pressor response to a voluntary hypoxic apnea.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Article
- Lower limb hyperthermia augments functional hyperaemia during small muscle mass exercise similarly in trained elderly and young humans.Experimental physiology · 2023Article
- Endothelial HSP72 is not reduced in type 2 diabetes nor is it a key determinant of endothelial insulin sensitivity.American journal of physiology. Regulatory, integrative and comparative physiology · 2022Article
- Regional thermal hyperemia in the human leg: Evidence of the importance of thermosensitive mechanisms in the control of the peripheral circulation.Physiological reports · 2021Article
- Influence of ischemia-reperfusion injury on endothelial function in men and women with similar serum estradiol concentrations.American journal of physiology. Regulatory, integrative and comparative physiology · 2021Article
- Sympathetic transduction in humans: recent advances and methodological considerations.American journal of physiology. Heart and circulatory physiology · 2021Review
- Hemodynamics of post-exercise vs. post hot water immersion recovery.Journal of applied physiology (Bethesda, Md. : 1985) · 2021Article
- Effect of endoplasmic reticulum stress on endothelial ischemia-reperfusion injury in humans.American journal of physiology. Regulatory, integrative and comparative physiology · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
There is a sustained reduction in arterial blood pressure that occurs in aged adults following exposure to acute leg heating. We tested the hypothesis that acute leg heating would decrease arterial blood pressure in aged adults secondary to sympathoinhibition. We exposed 13 young and 10 aged adults to 45 min of leg heating. Muscle sympathetic nerve activity (radial nerve) was measured before leg heating (preheat) and 30 min after (recovery) and is expressed as burst frequency. Neurovascular transduction was examined by assessing the slope of the relation between muscle sympathetic nerve activity and leg vascular conductance measured at rest and during isometric handgrip exercise performed to fatigue. Arterial blood pressure was well maintained in young adults (preheat, 86 ± 6 mmHg vs. recovery, 88 ± 7 mmHg;
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