Evidence map›Paper›PMID 32142258›Full record

ArticleAnalytical chemistry2020

A Benchtop Automated Sputum-to-Genotype System Using a Lab-on-a-Film Assembly for Detection of Multidrug-Resistant

Alexander V Kukhtin, Ryan Norville, Arial Bueno, Peter Qu, Nicole Parrish, Megan Murray, Darrell P Chandler, Rebecca C Holmberg, Christopher G Cooney

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Detecting rifampin and isoniazid resistance inJournal of clinical tuberculosis and other mycobacterial diseases · 2022
    Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexander V KukhtinAkonni Biosystems, Inc., 400 Sagner Avenue, Suite 300, Frederick, Maryland 21701, United States.
Ryan NorvilleAkonni Biosystems, Inc., 400 Sagner Avenue, Suite 300, Frederick, Maryland 21701, United States.
Arial BuenoAkonni Biosystems, Inc., 400 Sagner Avenue, Suite 300, Frederick, Maryland 21701, United States.
Peter QuAkonni Biosystems, Inc., 400 Sagner Avenue, Suite 300, Frederick, Maryland 21701, United States.
Nicole ParrishDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, United States.
Megan MurrayDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts 02115, United States.
Darrell P ChandlerAkonni Biosystems, Inc., 400 Sagner Avenue, Suite 300, Frederick, Maryland 21701, United States.
Rebecca C HolmbergAkonni Biosystems, Inc., 400 Sagner Avenue, Suite 300, Frederick, Maryland 21701, United States.
Christopher G CooneyAkonni Biosystems, Inc., 400 Sagner Avenue, Suite 300, Frederick, Maryland 21701, United States.ORCID 0000-0003-1583-545X

Funding

Sequencing CoreU19AI109755 · NIAID · HARVARD MEDICAL SCHOOL · PI CHANDLER, DARRELL P, CULHANE, AEDIN C · 2014 to 2018
$29.1M
An Integrated Tabletop Platform for Rapid Detection of XDR-TB in Clinical SamplesR01AI111435 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI RODWELL, TIMOTHY CHARLES · 2014 to 2018
$5.4M
TB Diagnostics at the Point of CareR44AI138903 · NIAID · AKONNI BIOSYSTEMS, INC. · PI COONEY, CHRISTOPHER GERARD · 2018 to 2020
$3.0M
Diagnostic array for aseptic encephalitisR44AI085650 · NIAID · AKONNI BIOSYSTEMS, INC. · PI CHANDLER, DARRELL P, COONEY, CHRISTOPHER GERARD · 2014 to 2016
$3.0M
TB Diagnostics at the Point of CareR44EB011274 · NIBIB · AKONNI BIOSYSTEMS, INC. · PI COONEY, CHRISTOPHER GERARD · 2013 to 2015
$1.2M
NIAID NIH HHS HHSN272201700001CNIAID NIH HHS HHSN272201700001GNIAID NIH HHS R01 AI111435NIAID NIH HHS R44 AI085650NIAID NIH HHS R44 AI138903NIAID NIH HHS U19 AI109755NIBIB NIH HHS R44 EB011274
6 · The paper itself

Abstract

Automated genotyping of drug-resistant

Indexed as

AutomationLab-On-A-Chip DevicesOptical ImagingGenotypeHumansMycobacterium tuberculosisSputumTuberculosis, Multidrug-Resistant

Identifiers

PMID32142258
PMCPMC7354060

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.