Evidence map›Paper›PMID 32141687›Full record

ArticlePediatric obesity2020

Temporal relationships between maternal metabolic parameters with neonatal adiposity in women with obesity differ by neonatal sex: Secondary analysis of the DALI study.

Rodrigo A Lima, Gernot Desoye, David Simmons, Roland Devlieger, Sander Galjaard, Rosa Corcoy, Juan M Adelantado, Fidelma Dunne, Jürgen Harreiter, Alexandra Kautzky-Willer and 14 more

Open access · hybridAbstract read
In one paragraph

Article in Pediatric obesity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

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  5. Molecular pathways in placental-fetal development and disruption.Molecular and cellular endocrinology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 16 institutions in 10 countries.

Rodrigo A LimaInstitute of Sport Science, University of Graz, Graz, Austria.ORCID 0000-0002-7778-2616
Gernot DesoyeDepartment of Obstetrics and Gynecology, Medizinische Universitaet Graz, Graz, Austria.
David SimmonsWestern Sydney University, Campbelltown, New South Wales, Australia.
Roland DevliegerKU Leuven Department of Development and Regeneration: Pregnancy, Fetus and Neonate, Gynaecology and Obstetrics, University Hospitals Leuven, Leuven, Belgium.
Sander GaljaardKU Leuven Department of Development and Regeneration: Pregnancy, Fetus and Neonate, Gynaecology and Obstetrics, University Hospitals Leuven, Leuven, Belgium.ORCID 0000-0002-4254-6664
Rosa CorcoyInstitut de Recerca de l'Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Juan M AdelantadoInstitut de Recerca de l'Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
Fidelma DunneGalway Diabetes Research Centre and College of Medicine Nursing and Health Sciences, National University of Ireland, Galway, Ireland.
Jürgen HarreiterGender Medicine Unit, Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Alexandra Kautzky-WillerGender Medicine Unit, Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
Peter DammCenter for Pregnant Women with Diabetes, Department of Endocrinology and Obstetrics, Rigshospitalet, Institute of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Elisabeth R MathiesenCenter for Pregnant Women with Diabetes, Department of Endocrinology and Obstetrics, Rigshospitalet, Institute of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Dorte M JensenSteno Diabetes Center Odense, Odense University Hospital, Odense, Denmark.
Lise-Lotte AndersenDepartment of Gynecology and Obstetrics, Odense University Hospital, Odense, Denmark.
Mette TanvigDepartment of Gynecology and Obstetrics, Odense University Hospital, Odense, Denmark.
Annunziata LapollaUniversita Degli Studi di Padova, Padua, Italy.
Maria G DalfraUniversita Degli Studi di Padova, Padua, Italy.
Alessandra BertolottoAzienda Ospedaliero Universitaria - Pisa, Pisa, Italy.
Ewa Wender-OzegowskaMedical Faculty I, Poznan University of Medical Sciences, Poznań, Poland.
Agnieszka ZawiejskaMedical Faculty I, Poznan University of Medical Sciences, Poznań, Poland.
David J HillRecherche en Santé Lawson SA, Bronschhofen, Switzerland.
Frank J SnoekDepartment of Medical Psychology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
Judith G M JelsmaDepartment of Public and Occupational Health, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Public Health research institute, Amsterdam, The Netherlands.
Mireille N M van PoppelInstitute of Sport Science, University of Graz, Graz, Austria.
University of Graz · ATMedical University of Vienna · ATPoznan University of Medical Sciences · PLUniversity of Copenhagen · DKUniversity of Padua · ITUniversity of Southern Denmark · DKAmsterdam Neuroscience · NLAmsterdam University Medical Centers · NLAzienda Ospedaliera Universitaria Pisana · ITCamden and Campbelltown Hospitals · AUErasmus MC · NLHospital de Sant Pau · ESInstituto de Salud Carlos III · ESKU Leuven · BEOllscoil na Gaillimhe – University of Galway · IESteno Diabetes Centers · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the importance of time in pregnancy and neonatal sex on the association between maternal metabolic parameters and neonatal sum of skinfolds.

methodsThis was a longitudinal, secondary analysis of the vitamin D and lifestyle intervention for gestational diabetes mellitus study, conducted in nine European countries during 2012 to 2015. Pregnant women with a pre-pregnancy body mass index (BMI) of ≥29 kg/m

resultsIn total, 458 mother-infant pairs (50.2% female infants) were included. Insulin resistance (fasting insulin and HOMA-index of insulin resistance) in early pregnancy was an important predictor for boys' sum of skinfolds, in addition to fasting glucose and maternal adiposity (leptin, BMI and neck circumference) throughout pregnancy. In girls, maternal lipids (triglycerides and fatty acids) in the first half of pregnancy were important predictors of sum of skinfolds, as well as fasting glucose in the second half of pregnancy.

conclusionsAssociations between maternal metabolic parameters and neonatal adiposity vary between different periods during pregnancy. This time-dependency is different between sexes, suggesting different growth strategies.

Indexed as

AdiposityAdultFemaleGestational AgeHumansInfant, NewbornLongitudinal StudiesMalePregnancyPregnancy in ObesitySex Characteristicsfoetal growthfoetal programmingmaternal healthmetabolic syndromeneonatal body compositionpregnancy

Identifiers

PMID32141687
PMCPMC7317347
OpenAlexW3009667990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.