ArticleMagnetic resonance in medicine2020
Systematic evaluation of velocity-selective arterial spin labeling settings for placental perfusion measurement.
Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- In Vivo Assessment of Placental Structure and Perfusion in Late-Gestation Pregnancies and Their Association With Fetal Growth.NMR in biomedicine · 2026Article
- Recent innovations in placental MRI: Integrating visualization and functional imaging.Placenta · 2026Review
- Assessment of Apparent Diffusion Coefficient and Perfusion Values of the Placenta in Intrauterine Growth Restriction by Using 3Tesla Magnetic Resonance Imaging (MRI) in an Indian Population: A Pilot Study.Ethiopian journal of health sciences · 2026Article
- Diffusion-T2 correlated spectroscopy imaging to explore possible placental composition changes over gestation.BMC medical imaging · 2025Article
- 3D Single Vessel Fractional Moving Blood Volume (3D-svFMBV): Fully Automated Tissue Perfusion Estimation Using Ultrasound.IEEE transactions on medical imaging · 2024Article
- Velocity-selective arterial spin labeling perfusion measurements in 2nd trimester human placenta with varying BMI.Placenta · 2024Article
- Advanced magnetic resonance imaging in human placenta: insights into fetal growth restriction and congenital heart disease.Frontiers in cardiovascular medicine · 2024Review
- Longitudinal assessment of placental perfusion in normal and hypertensive pregnancies using pseudo-continuous arterial spin-labeled MRI: preliminary experience.European radiology · 2023Article
- The human placenta project: Funded studies, imaging technologies, and future directions.Placenta · 2023Review
- Multi-modal MRI reveals changes in placental function following preterm premature rupture of membranes.Magnetic resonance in medicine · 2023Article
- Arterial spin labeling using spatio-temporal encoding readout for robust perfusion imaging in inhomogenous magnetic fields.Magnetic resonance in medicine · 2023Article
- Velocity-selective excitation: Principles and applications.NMR in biomedicine · 2023Review
- Dynamics of T2* and deformation in the placenta and myometrium during pre-labour contractions.Scientific reports · 2022Article
- Velocity-selective arterial spin labeling perfusion MRI: A review of the state of the art and recommendations for clinical implementation.Magnetic resonance in medicine · 2022Review
- Perfusion imaging of neuroblastoma and nephroblastoma in a paediatric population using pseudo-continuous arterial spin-labelling magnetic resonance imaging.Magma (New York, N.Y.) · 2022Article
- Fetal Neuroimaging Updates.Magnetic resonance imaging clinics of North America · 2021Review
- Exploring label dynamics of velocity-selective arterial spin labeling in the kidney.Magnetic resonance in medicine · 2021Article
- Systematic evaluation of velocity-selective arterial spin labeling settings for placental perfusion measurement.Magnetic resonance in medicine · 2020Article
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9 authors.
Funding
Abstract
purposePlacental function is key for successful human pregnancies. Perfusion may be a sensitive marker for the in vivo assessment of placental function. Arterial spin labeling (ASL) MRI enables noninvasive measurement of tissue perfusion and it was recently suggested that ASL with velocity-selective (VS) labeling could be advantageous in the placenta. We systematically evaluated essential VS-ASL sequence parameters to determine optimal settings for efficient placental perfusion measurements.
methodsEleven pregnant women were scanned at 3T using VS-ASL with 2D multislice echo planar imaging (EPI)-readout. One reference VS-ASL scan was acquired in all subjects; within subgroups the following parameters were systematically varied: cutoff velocity, velocity encoding direction, and inflow time. Visual evaluation and region of interest analyses were performed to compare perfusion signal differences between acquisitions.
resultsIn all subjects, a perfusion pattern with clear hyperintense focal regions was observed. Perfusion signal decreased with inflow time and cutoff velocity. Subject-specific dependence on velocity encoding direction was observed. High temporal signal-to-noise ratios with high contrast on the perfusion images between the hyperintense regions and placental tissue were seen at ~1.6 cm/s cutoff velocity and ~1000 ms inflow time. Evaluation of measurements at multiple inflow times revealed differences in blood flow dynamics between placental regions.
conclusionPlacental perfusion measurements are feasible at 3T using VS-ASL with 2D multislice EPI-readout. A clear dependence of perfusion signal on VS labeling parameters and inflow time was demonstrated. Whereas multiple parameter combinations may advance the interpretation of placental circulation dynamics, this study provides a basis to select an effective set of parameters for the observation of placenta perfusion natural history and its potential pathological changes.
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