Evidence map›Paper›PMID 32141462›Full record

ArticleOrganic & biomolecular chemistry2020

Total synthesis of isatindigotindoline C.

Juha H Siitonen, Sherlin Lira, Muhammed Yousufuddin, László Kürti

Abstract read
In one paragraph

Article in Organic & biomolecular chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Juha H SiitonenDepartment of Chemistry, Rice University, 6500 Main Street, Houston, TX 77030, USA. juha.siitonen@rice.edu laszlo.kurti@rice.edu.
Sherlin Lira
Muhammed Yousufuddin
László Kürti

Funding

Asymmetric N-H/N-alkyl olefin azirdinations and ring-opening transformationsR01GM114609 · NIGMS · RICE UNIVERSITY · PI KURTI, LASZLO · 2015 to 2018
$1.5M
NIGMS NIH HHS R01 GM114609
6 · The paper itself

Abstract

Total synthesis of isatindigotindoline C, a 3,3'-spiropyrrolidine oxindole alkaloid, is achieved in two steps using an exo-selective decarboxylative 1,3-dipolar cycloaddition as the key step. The synthesis verifies the originally assigned relative anti-stereochemistry for the bis-oxindole core of isatindigotindoline C.

Indexed as

Cycloaddition ReactionDecarboxylationIndole AlkaloidsOxindolesSpiro Compounds2-oxindoleIndole AlkaloidsOxindolesSpiro Compounds

Identifiers

PMID32141462
PMCPMC7341895

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.