ArticleInfection control and hospital epidemiology2020
Considerable variability in antibiotic use among US children's hospitals in 2017-2018.
Article in Infection control and hospital epidemiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 20 citations in OpenAlex.
- A Cautionary Tale of Combination Ceftriaxone and Lansoprazole: Should Pediatric Clinicians Heed the Warning?The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2025Article
- Use of antimicrobials in pediatric wards of five Brazilian hospitals.BMC pediatrics · 2024Observational
- Creating a Medication Therapy Observational Research Database from an Electronic Medical Record: Challenges and Data Curation.Applied clinical informatics · 2024Observational
- Protective effect of gut microbiota restored by fecal microbiota transplantation in a sepsis model in juvenile mice.Frontiers in immunology · 2024Article
- Appropriateness of antibiotic prescribing varies by clinical services at United States children's hospitals.Infection control and hospital epidemiology · 2023Article
- Patterns, Predictors, and Intercenter Variability in Empiric Gram-Negative Antibiotic Use Across 928 United States Hospitals.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- Variation in antibiotic use among neonatal intensive care units in the United States.Infection control and hospital epidemiology · 2022Article
- Assessment of Temporal Patterns and Patient Factors Associated With Oseltamivir Administration in Children Hospitalized With Influenza, 2007-2020.JAMA network open · 2022Article
- A Multicenter Analysis of Changes in Pediatric Antibiotic Susceptibilities AmongThe journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2022Article
- Antibiotic-Associated Adverse Events in Hospitalized Children.Journal of the Pediatric Infectious Diseases Society · 2021Observational
- Variability in Ceftriaxone Dosing Across 32 US Acute Care Children's Hospitals.Journal of the Pediatric Infectious Diseases Society · 2021Article
- A Hospital-Based Analytical Study on Antibiotic Utilization in Pediatric Patients and Antibiotic Stewardship.Journal of pharmacy & bioallied sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo characterize the prevalence of and seasonal and regional variation in inpatient antibiotic use among hospitalized US children in 2017-2018.
designWe conducted a cross-sectional examination of hospitalized children. The assessments were conducted on a single day in spring (May 3, 2017), summer (August 2, 2017), fall (October 25, 2017), and winter (January 31, 2018). The main outcome of interest was receipt of an antibiotic on the study day.
settingThe study included 51 freestanding US children's hospitals that participate in the Pediatric Health Information System (PHIS). PATIENTS: This study included all patients <18 years old who were admitted to a participating PHIS hospital, excluding patients who were admitted solely for research purposes.
resultsOf 52,769 total hospitalized children, 19,174 (36.3%) received antibiotics on the study day and 6,575 of these (12.5%) received broad-spectrum antibiotics. The overall prevalence of antibiotic use varied across hospitals from 22.3% to 51.9%. Antibiotic use prevalence was 29.2% among medical patients and 47.7% among surgical patients. Although there was no significant seasonal variation in antibiotic use prevalence, regional prevalence varied, ranging from 32.7% in the Midwest to 40.2% in the West (P < .001). Among units, pediatric intensive care unit patients had the highest prevalence of both overall and broad-spectrum antibiotic use at 58.3% and 26.6%, respectively (P < .001).
conclusionsOn any given day in a national network of children's hospitals, more than one-third of hospitalized children received an antibiotic, and 1 in 8 received a broad-spectrum antibiotic. Variation across hospitals, setting and regions identifies potential opportunities for enhanced antibiotic stewardship activities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.