Evidence map›Paper›PMID 32141131›Full record

ArticleMagnetic resonance in medicine2020

Towards unconstrained compartment modeling in white matter using diffusion-relaxation MRI with tensor-valued diffusion encoding.

Björn Lampinen, Filip Szczepankiewicz, Johan Mårtensson, Danielle van Westen, Oskar Hansson, Carl-Fredrik Westin, Markus Nilsson

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 93 citations in OpenAlex.

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  16. Surface-based Analyses of Diffusional Kurtosis Imaging in Amyotrophic Lateral Sclerosis: Relationship with Onset Subtypes.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025
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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Björn LampinenClinical Sciences Lund, Medical Radiation Physics, Lund University, Lund, Sweden.ORCID 0000-0001-8441-4443
Filip SzczepankiewiczClinical Sciences Lund, Radiology, Lund University, Lund, Sweden.ORCID 0000-0002-5251-587X
Johan MårtenssonClinical Sciences Lund, Department of Logopedics, Phoniatrics and Audiology, Lund University, Lund, Sweden.
Danielle van WestenClinical Sciences Lund, Radiology, Lund University, Lund, Sweden.
Oskar HanssonClinical Sciences Malmö, Clinical Memory Research Unit, Lund University, Lund, Sweden.
Carl-Fredrik WestinBrigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.
Markus NilssonClinical Sciences Lund, Radiology, Lund University, Lund, Sweden.ORCID 0000-0002-3140-8223
Lund University · SEBrigham and Women's Hospital · US

Funding

Training and DisseminationP41EB015902 · NIBIB · BRIGHAM AND WOMEN'S HOSPITAL · PI KIKINIS, RON, WESTIN, CARL-FREDRIK · 2012 to 2022
$20.9M
Novel DT-MRI Analyses of White Matter in SchizophreniaR01MH074794 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI WESTIN, CARL-FREDRIK · 2007 to 2021
$9.6M
Administrative Supplement Harmonization of At Risk Multisite Observational Networks for Youth(HARMONY)U01MH081928 · NIMH · BETH ISRAEL DEACONESS MEDICAL CENTER · PI STONE, WILLIAM SETH · 2008 to 2018
$7.1M
Next Generation Diffusion MRI Biomarkers for Prodromal SchizophreniaR01MH108574 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI PASTERNAK, OFER · 2016 to 2020
$2.2M
NIBIB NIH HHS P41 EB015902NIMH NIH HHS R01 MH074794NIMH NIH HHS R01 MH108574NIMH NIH HHS U01 MH081928
6 · The paper itself

Abstract

purposeTo optimize diffusion-relaxation MRI with tensor-valued diffusion encoding for precise estimation of compartment-specific fractions, diffusivities, and T

methodsSampling protocols featuring different b-values (b), b-tensor shapes (b

resultsPrecise parameter estimates were enabled by sampling protocols featuring seven or more "shells" with unique b/b

conclusionsDiffusion-relaxation MRI with tensor-valued diffusion encoding expands the set of microstructure parameters that can be precisely estimated and therefore increases their specificity to biological quantities.

Indexed as

White MatterAdultAgedBrainChildDiffusion Magnetic Resonance ImagingHumansbrain microstructurediffusion-relaxation MRIFisher informationtensor-valued diffusion encoding

Identifiers

PMID32141131
PMCPMC7652211
OpenAlexW3010073879

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.