Evidence map›Paper›PMID 32141068›Full record

ArticleClinical pharmacology and therapeutics2020

Predicting Inpatient Medication Orders From Electronic Health Record Data.

Kathryn Rough, Andrew M Dai, Kun Zhang, Yuan Xue, Laura M Vardoulakis, Claire Cui, Atul J Butte, Michael D Howell, Alvin Rajkomar

Abstract readComparative Study
In one paragraph

Article in Clinical pharmacology and therapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Graph representation and learning for drug administration prediction.BMC medical informatics and decision making · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Rethinking PICO in the Machine Learning Era: ML-PICO.Applied clinical informatics · 2021
    Article
  9. Review
  10. Article
  11. Article
  12. A learning pharmacy practice enabled by the pharmacists' patient care process.Journal of the American Pharmacists Association : JAPhA
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kathryn RoughGoogle, Mountain View, California, USA.
Andrew M DaiGoogle, Mountain View, California, USA.
Kun ZhangGoogle, Mountain View, California, USA.
Yuan XueGoogle, Mountain View, California, USA.
Laura M VardoulakisGoogle, Mountain View, California, USA.
Claire CuiGoogle, Mountain View, California, USA.
Atul J ButteBakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, California, USA.
Michael D HowellGoogle, Mountain View, California, USA.
Alvin RajkomarGoogle, Mountain View, California, USA.

Funding

Clinical and Translational Science InstituteUL1TR001872 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI COLLARD, HAROLD R, JACOBY, VANESSA · 2016 to 2025
$112.1M
NCATS NIH HHS UL1 TR001872
6 · The paper itself

Abstract

In a general inpatient population, we predicted patient-specific medication orders based on structured information in the electronic health record (EHR). Data on over three million medication orders from an academic medical center were used to train two machine-learning models: A deep learning sequence model and a logistic regression model. Both were compared with a baseline that ranked the most frequently ordered medications based on a patient's discharge hospital service and amount of time since admission. Models were trained to predict from 990 possible medications at the time of order entry. Fifty-five percent of medications ordered by physicians were ranked in the sequence model's top-10 predictions (logistic model: 49%) and 75% ranked in the top-25 (logistic model: 69%). Ninety-three percent of the sequence model's top-10 prediction sets contained at least one medication that physicians ordered within the next day. These findings demonstrate that medication orders can be predicted from information present in the EHR.

Indexed as

Deep LearningMachine LearningAcademic Medical CentersAdolescentAdultAgedAged, 80 and overElectronic Health RecordsFemaleHospitalizationHumansInpatientsLogistic ModelsMaleMedical Order Entry SystemsMiddle Aged

Identifiers

PMID32141068
PMCPMC7325318

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.