Evidence map›Paper›PMID 32141004›Full record

ArticleEnvironmental science and pollution research international2020

Characteristics of toxin production and release in Microcystis aeruginosa exposed to three tetracycline antibiotics.

Jing Ye, Chen Huang, Aihua Shang, Chao Xu, Liang Wu

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Toxicity of chlortetracycline and oxytetracycline on Vallisneria natans (Lour.) Hare.Environmental science and pollution research international · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Jing YeSchool of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai, 201418, China. yejinganna@163.com.
Chen HuangSchool of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai, 201418, China.
Aihua ShangSchool of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai, 201418, China.
Chao XuCollege of Environment, Zhejiang University of Technology, Hangzhou, 310032, China.
Liang WuDepartment of Chemical and Environmental Engineering, University of California, Riverside, Riverside, CA, 92521, USA.
Shanghai Institute of Technology · CNUniversity of California, Riverside · USZhejiang University of Technology · CN

Funding

National Natural Science Foundation of China 21307082The project of the Science and Technology Commission of Shanghai Municipality 18ZR1438000
6 · The paper itself

Abstract

The application of antibiotics is remarkable globally. However, antibiotic residues in aquatic ecosystems can pose adverse effects on nontarget plants and animals. In the present study, the cell growth properties and the production and release of microcystin-LR and microcystin-RR in cyanobacterium Microcystis aeruginosa after exposure to three typical antibiotics were investigated. Results showed that the order of the degree of chronic toxicities of the three chemicals was oxytetracycline hydrochloride (OTC) > tetracycline hydrochloride (TC) > chlortetracycline hydrochloride (CTC). The target antibiotics interfered with the production and release of the toxins microcystin-LR and microcystin-RR to varying degrees. TC simultaneously increased MC-LR intracellular and extracellular concentrations and interfered with MC-RR intracellular and extracellular concentrations to varying degrees. CTC reduced MC-LR intracellular concentrations and simultaneously reduced the MC-RR intracellular and extracellular concentrations. OTC increased the MC-LR intracellular and extracellular concentrations but did not have an effect on MC-RR concentrations. The extracellular MC-LR concentrations increased dramatically from day 24 to 27 when the cells were saturated, while most MC-RRs stayed within the cells. MC-LR can easily enter the surrounding water body and pose a threat when the water blooms occurred. Our results may help illustrate the influence of tetracycline antibiotics on the production and release of toxin in M. aeruginosa. It is important for environmental protection and evaluation. The results may as well guide the use of antibiotics in agricultural settings.

Indexed as

CyanobacteriaMicrocystisAnti-Bacterial AgentsEcosystemMicrocystinsTetracyclinesAnti-Bacterial AgentsMicrocystinsTetracyclinesMC-LRMC-RRMicrocystinsMicrocystis aeruginosaTetracycline antibioticsToxins

Identifiers

PMID32141004
OpenAlexW3010119273

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.