ArticleEndocrine2020
Leukocyte-related parameters in older adults with metabolic syndrome.
Article in Endocrine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Predictive role of neutrophil-to-lymphocyte ratio in metabolic syndrome: Meta-analysis of 70,937 individuals.BMC endocrine disorders · 2024Pooled it
- The association between white blood cell counts and metabolic health obesity among US adults.Frontiers in nutrition · 2025Article
- Multimorbidity patterns and the risk of falls among older adults: a community-based study in China.BMC geriatrics · 2024Article
- The role of peripheral white blood cell counts in the association between central adiposity and glycemic status.Nutrition & diabetes · 2024Article
- Multimorbidity patterns and health-related quality of life among community-dwelling older adults: evidence from a rural town in Suzhou, China.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Association between Metabolic Syndrome and Leukocytes: Systematic Review and Meta-Analysis.Journal of clinical medicine · 2023Review
- Investigating the relationship between haematological parameters and metabolic syndrome: A population-based study.Endocrinology, diabetes & metabolism · 2023Article
- Article
- The positive association between white blood cell count and metabolic syndrome is independent of insulin resistance among a Chinese population: a cross-sectional study.Frontiers in immunology · 2023Article
- Correlation of White Blood Cell, Neutrophils, and Hemoglobin with Metabolic Syndrome and Its Components.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- Comparison of Inflammatory Markers in the Diagnosis of Metabolic Syndrome in Hemodialysis Patients: A Multicenter Observational Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
- Monocyte to High-Density lipoprotein and Apolipoprotein A1 Ratios: Novel Indicators for Metabolic Syndrome in Chinese Newly Diagnosed Type 2 Diabetes.Frontiers in endocrinology · 2022Article
- Habitual tea consumption and 5-year incident metabolic syndrome among older adults: a community-based cohort study.BMC geriatrics · 2021Article
- Metabolic and immunological phenotype of rare lipomatoses: Dercum's disease and Roch-Leri mesosomatic lipomatosis.Orphanet journal of rare diseases · 2021Article
- The population characteristics of the main leukocyte subsets and their association with chronic diseases in a community-dwelling population: a cross-sectional study.Primary health care research & development · 2021Article
- Tea consumption and serum uric acid levels among older adults in three large-scale population-based studies in China.BMC geriatrics · 2021Article
- Leukocyte related parameters in older adults with metabolically healthy and unhealthy overweight or obesity.Scientific reports · 2021Article
- Platelet parameters in Chinese older adults with metabolic syndrome.Endocrine connections · 2020Article
- Metabolic Syndrome and 5-Year Incident Hyperuricemia Among Older Chinese Adults: A Community-Based Cohort Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
purposeWe aimed to examine the association between leukocyte-related parameters and the risk of metabolic syndrome (MetS) in community-dwelling older Chinese adults, with a special focus on assessing the diagnostic ability of leukocyte-related parameters in detecting MetS and the potential interaction effect of sex in the leukocyte-MetS relationship.
methodsStudy sample was from the Weitang Geriatric Diseases Study, which included 4579 individuals aged 60 years or above. MetS was diagnosed based on the Adult Treatment Panel III criteria. Leukocyte-related parameters were assessed using an automated hematology analyzer.
resultsThe adjusted odds ratio (95% confidence interval (CI)) of MetS for the highest quartile of leukocyte-related parameters (leukocyte, lymphocyte, neutrophil, monocyte, eosinophil, and basophil), when compared with the lowest quartile were 2.87 (2.30, 3.59), 2.69 (2.15, 3.36), 2.09 (1.67, 2.62), 2.12 (1.71, 2.64), 1.62 (1.31, 2.00), and 1.36 (1.11, 1.65), respectively. Adding leukocyte, lymphocyte, monocyte, and neutrophil to a model containing conventional risk factors improved risk prediction for MetS. Furthermore, significant interactions between leukocyte, monocyte, neutrophil, and sex on MetS were observed (all P value for interaction <0.01).
conclusionThe numbers of total leukocytes, lymphocyte, monocyte, neutrophil, and eosinophil counts were elevated in older adults with MetS, suggesting that leukocyte-related parameters may be meaningful biomarkers for MetS. Adding leukocyte-related parameters to the conventional models increased the ability of predicting MetS among older adults. These parameters may be useful biomarkers for further risk appraisal of MetS in older adults.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.