Evidence map›Paper›PMID 32140657›Full record

ArticleHepatology communications2020

The Transcription Factor Promyelocytic Leukemia Zinc Finger Protein Is Associated With Expression of Liver-Homing Receptors on Human Blood CD56

Leonard U Hess, Glòria Martrus, Annerose E Ziegler, Annika E Langeneckert, Wilhelm Salzberger, Hanna Goebels, Adrian F Sagebiel, Sven H Hagen, Tobias Poch, Gevitha Ravichandran and 9 more

Open access · goldAbstract read
In one paragraph

Article in Hepatology communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. The Dual Role of Natural Killer Cells in the Septic Liver.Journal of inflammation research · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Phenotypic and Functional Plasticity of CXCR6Frontiers in immunology · 2021
    Article
  11. Murine CXCR3Frontiers in immunology · 2021
    Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 2 countries.

Leonard U HessResearch Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.
Glòria MartrusResearch Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.
Annerose E ZieglerResearch Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.
Annika E LangeneckertResearch Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.
Wilhelm SalzbergerResearch Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.
Hanna GoebelsResearch Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.
Adrian F SagebielResearch Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.
Sven H HagenResearch Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.
Tobias PochFirst Medical Clinic and Polyclinic Center for Internal Medicine University Medical Center Hamburg-Eppendorf Hamburg Germany.
Gevitha RavichandranInstitute of Experimental Immunology and Hepatology University Medical Center Hamburg-Eppendorf Hamburg Germany.
Martina KochDivision of Transplantation Surgery University Medical Center of the Johannes Gutenberg University Mainz Germany.
Christoph SchrammFirst Medical Clinic and Polyclinic Center for Internal Medicine University Medical Center Hamburg-Eppendorf Hamburg Germany.
Karl J OldhaferDepartment of General and Abdominal Surgery Asklepios Hospital Barmbek Semmelweis University of Medicine Asklepios Campus Hamburg Germany.
Lutz FischerDepartment of Hepatobiliary Surgery and Transplant Surgery University Medical Center Hamburg-Eppendorf Hamburg Germany.
Gisa TiegsInstitute of Experimental Immunology and Hepatology University Medical Center Hamburg-Eppendorf Hamburg Germany.
Laura RichertResearch Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.
Madeleine J BundersResearch Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.
Sebastian LunemannResearch Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.
Marcus AltfeldResearch Department Virus Immunology Heinrich Pette Institute Leibniz Institute for Experimental Virology Hamburg Germany.
Leibniz Institute of Virology (LIV) · DEUniversität Hamburg · DEUniversity Medical Center Hamburg-Eppendorf · DEAsklepios Klinik Barmbek · DEUniversity Medical Center of the Johannes Gutenberg University Mainz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transcription factor promyelocytic leukemia zinc finger protein (PLZF) is involved in the development of natural killer (NK) cells and innate lymphoid cells, including liver-resident NK cells in mice. In human NK cells, the role of PLZF in liver residency is still unknown. Expression of PLZF in matched human peripheral blood- and liver-derived NK cells and the association of PLZF expression with surface molecules and transcription factors relevant for tissue residency were investigated using multiparameter flow cytometry and assessing single-cell messenger RNA (mRNA) levels. Intrahepatic cluster of differentiation (CD)56

Identifiers

PMID32140657
PMCPMC7049682
OpenAlexW2998245968

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.