Evidence map›Paper›PMID 32140628›Full record

ArticleClinical neurophysiology practice2020

The utility of sural-sparing pattern in the electrodiagnosis of regional subtypes of Guillain-Barré Syndrome.

Thirugnanam Umapathi, Jasmine S Koh, Y J Cheng, Eunice J H Goh, Christen S J Lim

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical neurophysiology practice, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Does COVID-19 cause axonal GBS?Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Thirugnanam UmapathiNational Neuroscience Institute, 11, Jalan Tan Tock Seng, Singapore 308433, Singapore.
Jasmine S KohNational Neuroscience Institute, 11, Jalan Tan Tock Seng, Singapore 308433, Singapore.
Y J ChengNational Neuroscience Institute, 11, Jalan Tan Tock Seng, Singapore 308433, Singapore.
Eunice J H GohNational Neuroscience Institute, 11, Jalan Tan Tock Seng, Singapore 308433, Singapore.
Christen S J LimNational Neuroscience Institute, 11, Jalan Tan Tock Seng, Singapore 308433, Singapore.
National Neuroscience Institute · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe present an exemplar patient, illustrating utility of the sural-sparing pattern in diagnosis of Guillain-Barré Syndrome (GBS). We then present data that sheds light on the pathophysiology of sural-sparing. METHOD AND

resultsWe describe a case of complex ophthalmoplegia that exemplifies the challenge of diagnosing regional subtypes of Guillain-Barré Syndrome, and the value of scrutinizing sensory nerve action potentials for the sural-sparing pattern. We also demonstrate, in a series of GBS patients, how serial nerve conduction studies can reveal "covert" sural-sparing in patients without sural-sparing on the initial study. Finally, by studying the median and radial sensory nerve action potentials at digit I in GBS patients, we demonstrate that the likely pathology of sural-sparing is related to the predilection of median nerve for subclinical entrapment; where the blood-nerve barrier is deficient and therefore more exposed to the immunopathology of GBS.

conclusionIncorporating sural-sparing would improve the specificity of GBS electrodiagnosis; especially in difficult to diagnose regional subtypes of GBS.

Indexed as

ElectrodiagnosisGuillain-Barré syndromeNerve conduction studySural-sparing pattern

Identifiers

PMID32140628
PMCPMC7044466
OpenAlexW3005303521

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.