ArticleHeliyon2020
A comparison of models for the analysis of the kinetics of drug release from PLGA-based nanoparticles.
Article in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
91 citing papers in PubMed.
- Photoactive Polyurethane Nanocomposites with Phloxine B‑Functionalized Poly(diallyldimethylammonium)-Saponite forACS omega · 2026Article
- The role of nanoparticles in the treatment of diabetic foot ulcers: mechanisms, delivery platforms, translational challenges, and future directions.Discover nano · 2026Review
- Development andACS omega · 2026Article
- Influence of Hydrothermal and Chemical Modifications of Potato Starch on Its Performance as a Carrier Matrix for Selected Polyphenolic Compound Derived from Chokeberry (Molecules (Basel, Switzerland) · 2026Article
- A Partition-Controlled Kinetic Model for Drug Release from Polymeric Nanocapsules: Resolving the Solubility Paradox.ACS pharmacology & translational science · 2026Article
- Rice Bran Wax-Based Matrix Tablets for Sustained Release of Diclofenac Sodium: Effects of Processing and Sintering.Pharmaceutics · 2026Article
- Light-Triggered and Sustained Delivery of Dexamethasone Using Chitosan-Coated PLGA Nanoparticles for Posterior Eye Disease Treatment.ACS omega · 2026Article
- PVA-Borax Hydrogels Loaded with Mono- and Bis-Spiro-Dioxy-Biphenyl-Cyclotriphosphazenes: Fabrication, Physicochemical Properties, and Release Kinetics.Molecules (Basel, Switzerland) · 2026Article
- Predicting drug release from polymeric long-acting injectables using a machine learning approach to decode formulation-performance relationships.Drug delivery and translational research · 2026Article
- Biomolecular Interfaces in Targeted Nano-Drug Delivery: Molecular Recognition, Signaling Modulation, and Translational Pathways.Biomolecules · 2026Review
- Electrosprayed PLGA Nanoparticles for Dual Drug Delivery: Design, Optimization and Applications.Polymers · 2026Review
- Encapsulation of Menthol in Bimodal Mesoporous Silica via Normal-Temperature and Alcohol-Thermal Loading Methods for Achieving Sustained Releasing Performances.Nanomaterials (Basel, Switzerland) · 2026Article
- Electrospun bi-layer carboxymethyl cellulose/polyvinyl alcohol/polycaprolactone nanofibers: fabrication, degradation, and phenytoin release kinetics.Scientific reports · 2026Article
- Quaternized Chitosan Crosslinked Networks for pH-Responsive Macromolecule Delivery: A Review.Polymers · 2026Review
- The Role of Cellulose Charge and Matrix Composition on KNOACS omega · 2026Article
- Development and Evaluation of Multiple-Unit Tablets for the Controlled Release of Lornoxicam.Drugs in R&D · 2026Article
- Bovine Colostrum-Derived Lactoferrin Nanoparticles as a Novel Platform for Improved Pulmonary Delivery of Osimertinib.Cell biochemistry and biophysics · 2026Article
- Oleic Acid-Coated Zinc Ferrite Nanocubes: A Promising Nanocarrier for Neuroblastoma Therapy.ACS omega · 2026Article
- AI-driven nanomedicine for cancer theranostics.Molecular cancer · 2026Review
- In vitro release kinetics and in vivo plasma exposure of green tea polyphenols and caffeine from iron oxide chitosan nanoparticles.Scientific reports · 2026Article
31 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePoly (lactic-co-glycolic acid) has received much academic attention for developing nanotherapeutics and FDA has approved it for several applications. An important parameter that dictates the bioavailability and hence the biological effect of the drug is drug release from its delivering system. This study offers a comparative mathematical analysis of drug release from Poly (lactic-co-glycolic acid)-based nanoparticles to suggest a general model explaining multi-mechanistic release they provide.
methodsEight release models, zero order, first order, Higuchi, Hixson-Crowell, the square root of mass, the three-second root of mass, Weibull and Korsmeyer-Peppas, as well as the second degree polynomial equation were applied to 60 data sets. The models analysed regarding several types of errors, regression parameters and average Akaike information criterion. RESULTS AND DISCUSSION: Most of the data sets present the highest R
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.