Evidence map›Paper›PMID 32140435›Full record

ArticleMethodsX2020

A protocol for metabolic characterization of human induced pluripotent stem cell-derived cardiomyocytes (iPS-CM).

Alisha House, Erica Fatica, Rohan Shah, Jared Stergar, Ryan Pearce, Yana Sandlers

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in MethodsX, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alisha HouseDepartment of Chemistry, Cleveland State University, Cleveland, OH 44115, United States.
Erica FaticaDepartment of Chemistry, Cleveland State University, Cleveland, OH 44115, United States.
Rohan ShahDepartment of Chemistry, Cleveland State University, Cleveland, OH 44115, United States.
Jared StergarDepartment of Chemistry, Cleveland State University, Cleveland, OH 44115, United States.
Ryan PearceDepartment of Chemistry, Cleveland State University, Cleveland, OH 44115, United States.
Yana SandlersDepartment of Chemistry, Cleveland State University, Cleveland, OH 44115, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent advances in human induced pluripotent stem cell-derived cardiomyocytes (iPSCM) field offer a novel platform for modeling cardiac metabolism, heart diseases drug candidates screening and cardiac toxicity assessments. These workflows require a fully functional characterization of iPSCMs. Here we report a step by step protocol for iPSCM metabolic characterization. The described assays cover analysis of small metabolites involved in a vital metabolic pathways.

Indexed as

GCMSInduced pluripotent stem cell-derived cardiomyocytesLC–MS/MSMetabolic characterization

Identifiers

PMID32140435
PMCPMC7046813

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.