Evidence map›Paper›PMID 32140254›Full record

ArticleGlobal challenges (Hoboken, NJ)2020

Size-Independent Transmembrane Transporting of Single Tetrahedral DNA Nanostructures.

Xi Chen, Falin Tian, Min Li, Haijiao Xu, Mingjun Cai, Qian Li, Xiaolei Zuo, Hongda Wang, Xinghua Shi, Chunhai Fan and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Global challenges (Hoboken, NJ), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Nucleic acid nanostructures forApplied physics reviews · 2023
    Review
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Xi ChenSchool of Chemistry and Life Science Advanced Institute of Materials Science Changchun University of Technology Changchun Jilin 130012 China.
Falin TianLaboratory of Theoretical and Computational Nanoscience CAS Key Laboratory for Nanosystem and Hierarchy Fabrication CAS Center for Excellence in Nanoscience National Center for Nanoscience and Technology Chinese Academy of Sciences Beijing 100190 China.
Min LiSchool of Chemistry and Chemical Engineering and Institute of Molecular Medicine Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai 200240 China.
Haijiao XuState Key Laboratory of Electroanalytical Chemistry Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun Jilin 130022 China.
Mingjun CaiState Key Laboratory of Electroanalytical Chemistry Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun Jilin 130022 China.
Qian LiSchool of Chemistry and Chemical Engineering and Institute of Molecular Medicine Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai 200240 China.
Xiaolei ZuoSchool of Chemistry and Chemical Engineering and Institute of Molecular Medicine Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai 200240 China.
Hongda WangState Key Laboratory of Electroanalytical Chemistry Changchun Institute of Applied Chemistry Chinese Academy of Sciences Changchun Jilin 130022 China.
Xinghua ShiLaboratory of Theoretical and Computational Nanoscience CAS Key Laboratory for Nanosystem and Hierarchy Fabrication CAS Center for Excellence in Nanoscience National Center for Nanoscience and Technology Chinese Academy of Sciences Beijing 100190 China.
Chunhai FanSchool of Chemistry and Chemical Engineering and Institute of Molecular Medicine Renji Hospital School of Medicine Shanghai Jiao Tong University Shanghai 200240 China.
Huricha BaigudeSchool of Chemistry & Chemical Engineering Inner Mongolia Key Laboratory of Mongolian Medicinal Chemistry Inner Mongolia University Hohhot Inner Mongolia 010020 China.
Yuping ShanSchool of Chemistry and Life Science Advanced Institute of Materials Science Changchun University of Technology Changchun Jilin 130012 China.ORCID https://orcid.org/0000-0002-3827-7123
Chinese Academy of Sciences · CNShanghai Jiao Tong University · CNChangchun Institute of Technology · CNInner Mongolia University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA nanostructures have attracted considerable attention as drug delivery carriers. However, the transmembrane kinetics of DNA nanostructures remains less explored. Herein, the dynamic process of transporting single tetrahedral DNA nanostructures (TDNs) is monitored in real time using a force-tracing technique based on atomic force microscopy. The results show that transporting single TDNs into living HeLa cells need ≈53 pN force and ≈25 ms duration with the average speed of ≈0.6 µm s

Indexed as

force tracingreal‐time trackingsingle tetrahedral DNA nanostructurestransmembrane kinetics

Identifiers

PMID32140254
PMCPMC7050086
OpenAlexW2990674687

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.