Evidence map›Paper›PMID 32140189›Full record

ReviewThe EPMA journal2020

Colorectal cancer in Saudi Arabia as the proof-of-principle model for implementing strategies of predictive, preventive, and personalized medicine in healthcare.

Mesnad Alyabsi, Abdulrahman Alhumaid, Haafiz Allah-Bakhsh, Mohammed Alkelya, Mohammad Azhar Aziz

Open access · greenAbstract readReview
In one paragraph

Review in The EPMA journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. IncreasedPharmaceuticals (Basel, Switzerland) · 2024
    Article
  8. Article
  9. Real-life experiences and barriers to adjuvant chemotherapy in Saudi patients with advanced stage II and stage III colon cancer.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2024
    Article
  10. Article
  11. Heliyon · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Higher Expression Levels ofMedicina (Kaunas, Lithuania) · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Mesnad Alyabsi1Population Health Research Section, King Abdullah International Medical Research Center, P.O. Box 22490, Riyadh, 11426 Saudi Arabia.ORCID 0000-0001-7763-9572
Abdulrahman Alhumaid3King Faisal Specialist Hospital and Research Center, Riyadh, 12713 Saudi Arabia.ORCID 0000-0001-5759-002X
Haafiz Allah-Bakhsh4Department of Organ Transplant & Hepatobiliary Surgery, Ministry of National Guard Health Affairs, King Abdullah International Medical Research Center, P.O. Box 22490, Riyadh, 11426 Saudi Arabia.ORCID 0000-0002-8532-8085
Mohammed Alkelya1Population Health Research Section, King Abdullah International Medical Research Center, P.O. Box 22490, Riyadh, 11426 Saudi Arabia.ORCID 0000-0002-9431-3280
Mohammad Azhar Aziz1Population Health Research Section, King Abdullah International Medical Research Center, P.O. Box 22490, Riyadh, 11426 Saudi Arabia.ORCID 0000-0002-0798-5063
King Saud bin Abdulaziz University for Health Sciences · SAKing Abdullah International Medical Research Center · SAKing Faisal Specialist Hospital & Research Centre · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is the most commonly diagnosed cancer among Saudi males and ranks third in females with up to 73% of cases diagnosed at late stage. This review provides an analysis of CRC situation in the Kingdom of Saudi Arabia (KSA) from healthcare perspective. A PUBMED (1986-2018) search was done to identify publications focusing on CRC in KSA. Due to reports of increased CRC incidence among young age group (< 50), and given the young population of KSA, the disease may burden the national healthcare system in the next decades. Environmental factors attributed to increasing incidence rates of CRC include red meat consumption, sedentary lifestyle, and increased calorie intake. Despite substantial investment in healthcare, attention to predictive diagnostics and targeted prevention is lacking. There is a need to develop national screening guidelines based on evidence that supports a reduction in incidence and mortality of CRC when screening is implemented. Future approaches are discussed based on multi-level diagnostics, risk assessment, and population screening programs focused on the needs of young populations that among others present the contents of the advanced approach by predictive, preventive, and personalized medicine. Recommendations are provided that could help to develop policies at regional and national levels. Countries with demographics and lifestyle similar to KSA may gain insights from this review to shape their policies and procedures.

Indexed as

Personalized patient profilingPredictive preventive personalized medicine, colorectal cancerRisk factorsSaudi ArabiaScreeningTargeted prevention, healthcare strategy, biomarkersTreatment tailored to the personYoung population

Identifiers

PMID32140189
PMCPMC7028887
OpenAlexW2970702631

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.