ArticleJournal of occupational medicine and toxicology (London, England)2020
Heart rate variability and cardiac repolarization after exposure to zinc oxide nanoparticles in healthy adults.
Article in Journal of occupational medicine and toxicology (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 7 citations in OpenAlex.
- Systemic inflammatory effects of zinc oxide particles: is a re-evaluation of exposure limits needed?Archives of toxicology · 2023Article
- The human long noncoding RNAs CoroMarker, MALAT1, CDR1as, and LINC00460 in whole blood of individuals after controlled short-term exposure with ultrafine metal fume particles at workplace conditions, and in human macrophages in vitro.Journal of occupational medicine and toxicology (London, England) · 2022Article
- ZnO Nanoparticles Induce Dyslipidemia and Atherosclerotic Lesions Leading to Changes in Vascular Contractility and Cannabinoid Receptors Expression as Well as Increased Blood Pressure.Nanomaterials (Basel, Switzerland) · 2021Article
- Cell-biological effects of zinc oxide spheres and rods from the nano- to the microscale at sub-toxic levels.Cell biology and toxicology · 2021Article
- Health effects after inhalation of micro- and nano-sized zinc oxide particles in human volunteers.Archives of toxicology · 2021Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExposure to airborne zinc oxide (ZnO) particles occurs in many industrial processes, especially in galvanizing and welding. Systemic inflammation after experimental inhalation of ZnO particles has been demonstrated previously, but little is known about the impact on the cardiovascular system, particularly on the autonomic cardiac system and the risk of arrhythmias. In this study we investigated the short-term effects of ZnO nanoparticles on heart rate variability (HRV) and repolarization in healthy adults in a concentration-dependent manner at rest and during exercise in a controlled experimental set-up.
methodsSixteen healthy subjects were exposed to filtered air and ZnO particles (0.5, 1.0 and 2.0 mg/m
resultsOverall, no statistically significant effects of controlled ZnO inhalation on HRV parameters and QT interval were observed. Additionally, a concentration-response was absent.
conclusionInhalation of ZnO nanoparticles up to 2.0 mg/m
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Registered trials
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