Evidence map›Paper›PMID 32140172›Full record

ArticleFrontiers in genetics2020

Downregulation of miR-26b-5p, miR-204-5p, and miR-497-3p Expression Facilitates Exercise-Induced Physiological Cardiac Hypertrophy by Augmenting Autophagy in Rats.

Jie Qi, Xue Luo, Zhichao Ma, Bo Zhang, Shuyan Li, Jun Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
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  6. Article
  7. Epigenetic Mechanisms in Heart Diseases.Reviews in cardiovascular medicine · 2025
    Review
  8. Exosomes and microRNAs as mediators of the exercise.European journal of medical research · 2025
    Review
  9. Review
  10. Reports of biochemistry & molecular biology · 2024
    Article
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  13. Review
  14. Article
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Jie QiCollege of Physical Education, Shanghai Normal University, Shanghai, China.
Xue LuoMedical College, Yangzhou Polytechnic College, Yangzhou, China.
Zhichao MaThe School of Physical Education, Wuhan Business University, Wuhan, China.
Bo ZhangCollege of Physical Education, Shanghai Normal University, Shanghai, China.
Shuyan LiCollege of Physical Education, Yangzhou University, Yangzhou, China.
Jun ZhangCollege of Physical Education, Shanghai Normal University, Shanghai, China.
Shanghai Normal University · CNWuhan Business University · CNYangzhou Polytechnic Institute · CNYangzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exercise-induced autophagy is associated with physiological left ventricular hypertrophy (LVH), and a growing body of evidence suggests that microRNAs (miRNAs) can regulate autophagy-related genes. However, the precise role of miRNAs in exercise induced autophagy in physiological LVH has not been fully defined. In this study, we investigated the microRNA-autophagy axis in physiological LVH and deciphered the underlying mechanism using a rat swimming exercise model. Rats were assigned to sedentary control (CON) and swimming exercise (EX) groups; those in the latter group completed a 10-week swimming exercise without any load. For

Indexed as

autophagycardiac hypertrophyexerciseinsulin-like growth factor 1microRNA

Identifiers

PMID32140172
PMCPMC7042403
OpenAlexW3007375980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.