Evidence map›Paper›PMID 32140074›Full record

ArticleInternational journal of biological sciences2020

The CARM1-p300-c-Myc-Max (CPCM) transcriptional complex regulates the expression of

Wenzhu Lu, Chunmei Yang, Hongbo He, Hong Liu

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
  2. Targeting c-Myc-p300-CARM1 complex induces ferroptosis and reduces CD8International journal of biological sciences · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. PRMT3 and CARM1: Emerging Epigenetic Targets in Cancer.Journal of cellular and molecular medicine · 2025
    Review
  7. Review
  8. Article
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  10. Review
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  12. Article
  13. Significant position of C-myc in colorectal cancer: a promising therapeutic target.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022
    Review
  14. Article
  15. Article
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  17. Review
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  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Wenzhu LuDepartment of Integrated Traditional and Western Medicine, West China Hospital of Sichuan University, Chengdu 610041, Sichuan, China.
Chunmei YangDepartment of Integrated Traditional and Western Medicine, Chengdu Shangjinnanfu Hospital/West China Hospital of Sichuan University, Chengdu 610041, Sichuan, China.
Hongbo HeDepartment of Integrated Traditional and Western Medicine, West China Hospital of Sichuan University, Chengdu 610041, Sichuan, China.
Hong LiuDepartment of Integrated Traditional and Western Medicine, West China Hospital of Sichuan University, Chengdu 610041, Sichuan, China.
West China Hospital of Sichuan University · CNSichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transcription factor c-Myc and two cullin family members CUL4A/4B function as oncogenes in colorectal cancer. Our recent publication reveals that c-Myc specifically activates the expression of

Indexed as

Cell Line, TumorCell ProliferationColorectal NeoplasmsCullin ProteinsE1A-Associated p300 ProteinHCT116 CellsHT29 CellsHumansImmunoprecipitationMass SpectrometryProtein-Arginine N-MethyltransferasesProto-Oncogene Proteins c-mycUbiquitinationUbiquitin-Protein Ligasescoactivator-associated arginine methyltransferase 1CUL4A protein, humanCUL4B protein, humanCullin ProteinsE1A-Associated p300 ProteinEP300 protein, humanProtein-Arginine N-MethyltransferasesProto-Oncogene Proteins c-mycUbiquitin-Protein LigasesCARM1colorectal cancerCRL4 E3 ligaseCUL4ACUL4Bp300

Identifiers

PMID32140074
PMCPMC7053342
OpenAlexW3005800239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.