ReviewActa pharmacologica Sinica2020
Psychosis in Parkinson's disease and parkinsonism in antipsychotic-naive schizophrenia spectrum psychosis: clinical, nosological and pathobiological challenges.
Review in Acta pharmacologica Sinica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 35 citations in OpenAlex.
- Disrupted neural response timing and duration during hand movement preparation in schizophrenia spectrum disorder: An fMRI study.Scientific reports · 2026Article
- Temporal assessment of behavior in Parkinson's visual hallucinations via a multidimensional analysis strategy.Signal transduction and targeted therapy · 2026Article
- Temporal characteristics of hemodynamic responses during active and passive hand movements in schizophrenia spectrum disorder.Schizophrenia (Heidelberg, Germany) · 2025Article
- Parkinsonism, Psychomotor Slowing, Negative and Depressive Symptoms in Schizophrenia Spectrum and Mood Disorders: Exploring Their Intricate Nexus Using a Network Analytic Approach.Schizophrenia bulletin · 2025Article
- Gait Disturbance in Patients with Schizophrenia in Relation to Walking Speed, Ankle Joint Range of Motion, Body Composition, and Extrapyramidal Symptoms.Healthcare (Basel, Switzerland) · 2025Article
- Aberrant preparation of hand movement in schizophrenia spectrum disorder: an fMRI study.Brain communications · 2025Article
- Article
- Facial and upper-limb movement abnormalities in individuals with psychotic-like experiences: a motion analysis study.European archives of psychiatry and clinical neuroscience · 2023Article
- Inflammation, Dopaminergic Brain and Bilirubin.International journal of molecular sciences · 2023Review
- Characterizing the sensorimotor domain in schizophrenia spectrum disorders.European archives of psychiatry and clinical neuroscience · 2022Article
- Extrapyramidal symptoms predict cognitive performance after first-episode psychosis.Schizophrenia (Heidelberg, Germany) · 2022Article
- Probable progressive supranuclear palsy in a patient with chronic schizophrenia: A case report.Experimental and therapeutic medicine · 2022Article
- Motor Behavior is Relevant for Understanding Mechanism, Bolstering Prediction, And Improving Treatment: A Transdiagnostic Perspective.Schizophrenia bulletin · 2022Article
- RNA-seq analysis of gene expression profiles in posttraumatic stress disorder, Parkinson's disease and schizophrenia identifies roles for common and distinct biological pathways.Discover mental health · 2022Article
- Psychomotor Symptoms in Chronic Cocaine Users: An Interpretative Model.International journal of environmental research and public health · 2022Article
- Structural alterations in brainstem, basal ganglia and thalamus associated with parkinsonism in schizophrenia spectrum disorders.European archives of psychiatry and clinical neuroscience · 2021Article
- Why is there symptom coupling of psychological and motor changes in psychomotor mechanisms? Insights from the brain's topography.Molecular psychiatry · 2021Article
- All roads lead to the motor cortex: psychomotor mechanisms and their biochemical modulation in psychiatric disorders.Molecular psychiatry · 2021Review
- Using Virtual Reality as a Tool in the Rehabilitation of Movement Abnormalities in Schizophrenia.Frontiers in psychology · 2020Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Following the formulation of operational criteria for the diagnosis of psychosis in Parkinson's disease, a neurodegenerative disorder, the past decade has seen increasing interest in such nonmotor psychopathology that appears to be independent of dopaminergic therapy. Similarly, there has been a resurgence of interest in motor aspects of the neurodevelopmental disorder of schizophrenia, including spontaneous parkinsonism that appears to be independent of antipsychotic treatment. This review first addresses the clinical and nosological challenges of these superficially paradoxical insights and then considers pathobiological challenges. It proposes that diverse modes of disturbance to one or more element(s) in a cortical-striatal-thalamocortical neuronal network, whether neurodegenerative or neurodevelopmental, can result in movement disorder, psychosis or both. It then proposes that time- and site-dependent dysfunction in such a neuronal network may be a generic substrate for the emergence of psychosis not only in Parkinson's disease and schizophrenia-spectrum disorders but also in other neuropsychiatric disorders in which psychosis, and sometimes movement disorders, can be encountered; these include substance abuse, cerebrovascular disease, cerebral trauma, cerebral neoplasia, epilepsy, Huntington's disease, frontotemporal dementia, Alzheimer's disease and multiple sclerosis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.