Evidence map›Paper›PMID 32139661›Full record

ArticleAging2020

Genetic variants in

Yang Wang, Qian Jiang, Hao Cai, Ze Xu, Wenjie Wu, Beilin Gu, Long Li, Wei Cai

Open access · greenAbstract read
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Role of ARHGEF3 as a GEF and mTORC2 Regulator.Frontiers in cell and developmental biology · 2021
    Review
  8. Negative Association Between lncRNAPharmacogenomics and personalized medicine · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yang WangDepartment of Pediatric Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Qian JiangDepartment of Medical Genetics, Capital Institute of Pediatrics, Beijing, China.
Hao CaiDepartment of Pediatric Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Ze XuDepartment of Pediatric Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Wenjie WuDepartment of Pediatric Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Beilin GuDepartment of Pediatric Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Long LiDepartment of General Surgery, Capital Institute of Pediatrics Affiliated Children's Hospital, Beijing, China.
Wei CaiDepartment of Pediatric Surgery, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Shanghai Institute of Nutrition and Health · CNShanghai Jiao Tong University · CNCapital Institute of Pediatrics · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hirschsprung disease (HSCR), the most common enteric neuropathy, stands as a model for complex genetic disorders. It has recently been demonstrated that both

Indexed as

alpha CateninAsian PeopleCase-Control StudiesChildChild, PreschoolFemaleGene Regulatory NetworksGenetic Predisposition to DiseaseGenotypeHaplotypesHirschsprung DiseaseHumansInfantLinkage DisequilibriumMalePolymorphism, Single Nucleotidealpha CateninARHGEF3 protein, humanCTNNAL1 protein, humanProto-Oncogene Proteins c-retReelin ProteinRELN protein, humanRET protein, humanRho Guanine Nucleotide Exchange FactorsARHGEF3CTNNAL1genetic interaction networksHirschsprung diseaseRET

Identifiers

PMID32139661
PMCPMC7093166
OpenAlexW3009998757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.