Evidence map›Paper›PMID 32139586›Full record

ArticleScience immunology2020

Origins and clonal convergence of gastrointestinal IgE

Ramona A Hoh, Shilpa A Joshi, Ji-Yeun Lee, Brock A Martin, Sushama Varma, Shirley Kwok, Sandra C A Nielsen, Parastu Nejad, Emily Haraguchi, Priya S Dixit and 16 more

Open access · greenAbstract read
In one paragraph

Article in Science immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 129 citations in OpenAlex.

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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

26 authors at 4 institutions in 1 country.

Ramona A HohDepartment of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-5116-1942
Shilpa A JoshiDepartment of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-8014-1529
Ji-Yeun LeeDepartment of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-0463-6802
Brock A MartinDepartment of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Sushama VarmaDepartment of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Shirley KwokDepartment of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Sandra C A NielsenDepartment of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0003-4746-8287
Parastu NejadDepartment of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Emily HaraguchiDepartment of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Priya S DixitDepartment of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Swetha V ShutthanandanDepartment of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Krishna M RoskinDepartment of Pediatrics, University of Cincinnati, College of Medicine, Cincinnati, OH 45267, USA.ORCID 0000-0002-5864-5093
Wenming ZhangSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA 94305, USA.
Dana TupaSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-0048-416X
Bryan J BunningSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA 94305, USA.
Monali ManoharSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA 94305, USA.
Robert TibshiraniDepartment of Biomedical Data Sciences, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0003-0553-5090
Nielsen Q Fernandez-BeckerDivision of Gastroenterology and Hepatology, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.
Neeraja KambhamDepartment of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0003-1136-3686
Robert B WestDepartment of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-8330-8283
Robert G HamiltonDivision of Allergy and Clinical Immunology, Department of Medicine, and Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Mindy TsaiDepartment of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.
Stephen J GalliDepartment of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0001-5736-5340
Rebecca S ChinthrajahSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA 94305, USA.
Kari C NadeauSean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-2146-2955
Scott D BoydDepartment of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA. sboyd1@stanford.edu.ORCID 0000-0003-0963-044X
Stanford University · USPulmonary and Allergy Associates · USCincinnati Children's Hospital Medical Center · USJohns Hopkins University · US

Funding

Tracking allergen specific T cells in multi-food allergyU19AI104209 · NIAID · STANFORD UNIVERSITY · PI GALLI, STEPHEN JOSEPH · 2013 to 2025
$17.3M
SEAL (Stopping Atopic dermatitis and ALlergy) Study: Prevent allergy by enhancing the skin barrierU01AI147462 · NIAID · STANFORD UNIVERSITY · PI Mary Johnson, GIDEON LACK · 2020 to 2026
$14.0M
Effects of aging on primary and secondary vaccine responses in a 15-year longitudinal cohortR01AI130398 · NIAID · STANFORD UNIVERSITY · PI BOYD, SCOTT DEXTER · 2017 to 2021
$4.0M
FUNCTIONAL ANALYSIS OF PATHOGENIC AND PROTECTIVE PEANUT ALLERGEN-SPECIFIC HUMAN ANTIBODIESR01AI125567 · NIAID · STANFORD UNIVERSITY · PI BOYD, SCOTT DEXTER · 2017 to 2022
$2.6M
Secondhand smoke and asthma: Mechanistic outcomes of DNA methylation in T cellsR01HL118612 · NHLBI · STANFORD UNIVERSITY · PI MILLER, RACHEL L, NADEAU, KARI C. · 2014 to 2017
$2.3M
Storage and recall of human B cell memory of influenza over tissues and timeR01AI127877 · NIAID · STANFORD UNIVERSITY · PI BOYD, SCOTT DEXTER · 2017 to 2021
$2.0M
T Cell Reagent Research for Monitoring T Cell in Food AllergyU01AI140498 · NIAID · STANFORD UNIVERSITY · PI NADEAU, KARI C. · 2018 to 2022
$1.8M
Evaluating the role of allergen dose and duration in the safety and efficacy of multi-allergen oral immunotherapy with OmalizumabUM1AI130839 · NIAID · STANFORD UNIVERSITY · PI CHINTHRAJAH, R. SHARON · 2017 to 2023
$1.6M
Effects of IgE Blockade on T Cells in Food AllergyR01AI140134 · NIAID · STANFORD UNIVERSITY · PI NADEAU, KARI C. · 2018 to 2021
$1.6M
NHLBI NIH HHS R01 HL118612NIAID NIH HHS R01 AI125567NIAID NIH HHS R01 AI127877NIAID NIH HHS R01 AI130398NIAID NIH HHS R01 AI140134NIAID NIH HHS U01 AI140498NIAID NIH HHS U01 AI147462NIAID NIH HHS U19 AI104209NIAID NIH HHS UM1 AI130839
6 · The paper itself

Abstract

B cells in human food allergy have been studied predominantly in the blood. Little is known about IgE

Indexed as

2S Albumins, PlantAdultAntigens, PlantB-LymphocytesFemaleGastrointestinal TractHigh-Throughput Nucleotide SequencingHumansImmobilized Nucleic AcidsImmunoglobulin EMaleMiddle AgedPeanut Hypersensitivity2S Albumins, PlantAntigens, PlantAra h 2 allergen, Arachis hypogaeaImmobilized Nucleic AcidsImmunoglobulin E

Identifiers

PMID32139586
PMCPMC7691169
OpenAlexW3010519369

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.