Evidence map›Paper›PMID 32139546›Full record

ArticleScience (New York, N.Y.)2020

PE/PPE proteins mediate nutrient transport across the outer membrane of

Qinglan Wang, Helena I M Boshoff, Justin R Harrison, Peter C Ray, Simon R Green, Paul G Wyatt, Clifton E Barry

Open access · greenAbstract read
In one paragraph

Article in Science (New York, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
128citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

128 citing papers in PubMed, 1 synthesis or guideline pooled it, 194 citations in OpenAlex.

  1. Pooled it
  2. The mycomembrane proteins PorH and ProtX are inserted at polar growth zones and linked to the cell wall.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
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  6. Article
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  9. Tyloxapol inhibits ESX-1 secretion inJournal of bacteriology · 2026
    Article
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  14. Non-canonical peptidoglycan cross-linking is essential forbioRxiv : the preprint server for biology · 2026
    Article
  15. ThemBio · 2026
    Article
  16. ARNA (New York, N.Y.) · 2026
    Article
  17. Article
  18. Recent Characterization of Key Proteins to Combat Tuberculosis.Advances in experimental medicine and biology · 2026
    Review
  19. Article
  20. Review

68 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Qinglan WangTuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0002-7629-5058
Helena I M BoshoffTuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.ORCID 0000-0002-4333-206X
Justin R HarrisonDrug Discovery Unit, College of Life Sciences, James Black Centre, University of Dundee, Dundee DD1 5EH, UK.
Peter C RayDrug Discovery Unit, College of Life Sciences, James Black Centre, University of Dundee, Dundee DD1 5EH, UK.ORCID 0000-0002-7828-0853
Simon R GreenDrug Discovery Unit, College of Life Sciences, James Black Centre, University of Dundee, Dundee DD1 5EH, UK.ORCID 0000-0001-5054-4792
Paul G WyattDrug Discovery Unit, College of Life Sciences, James Black Centre, University of Dundee, Dundee DD1 5EH, UK.ORCID 0000-0002-0397-245X
Clifton E BarryTuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA. cbarry@niaid.nih.gov.ORCID 0000-0002-2927-270X
University of Dundee · GBNational Institutes of Health · US

Funding

Development Of New Chemotherapeutics For TuberculosisZIAAI000693 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI BARRY, CLIFTON · 2009 to 2025
$20.1M
PATHOGENIC MECHANISMS OF MYCOBACTERIUM TUBERCULOSISZ01AI000693 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI BARRY, CLIFTON · 1993 to 2008
$8.1M
Intramural NIH HHS Z01 AI000693Wellcome Trust 203134/Z/16/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AmidesBacterial ProteinsBiological TransportCell MembraneCell Membrane PermeabilityDrug Resistance, BacterialGene DeletionGlucoseGlycerolLipidsMycobacterium tuberculosisSulfhydryl CompoundsAmidesBacterial ProteinsGlucoseGlycerolLipidsphthiocerol dimycocerosatepropionamideSulfhydryl Compounds

Identifiers

PMID32139546
PMCPMC11036889
OpenAlexW3010069454

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.