Evidence map›Paper›PMID 32139453›Full record

ArticleBMJ case reports2020

Steroids as rescue therapy for vitamin A-induced acute liver failure.

Anand V Kulkarni, Pramod Kumar, Rupjyoti Talukdar, Nagaraj P Rao

Open access · bronzeAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anand V KulkarniDepartment of Hepatology, Asian Institute of Gastroenterology, Hyderabad, India anandvk90@gmail.com.ORCID http://orcid.org/0000-0002-1240-1675
Pramod KumarDepartment of Hepatology, Asian Institute of Gastroenterology, Hyderabad, India.
Rupjyoti TalukdarDepartment of Pancreatology, Asian Institute of Gastroenterology, Hyderabad, India.
Nagaraj P RaoDepartment of Hepatology, Asian Institute of Gastroenterology, Hyderabad, India.
Asian Institute of Gastroenterology · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antioxidant drugs form one of the mainstay therapies for pain management in chronic pancreatitis. Heightened oxidative stress and free radical activity is the target for the use of antioxidant therapy in chronic pancreatitis pain relief. One of the chief components of these drugs is beta-carotene, and vitamin A. Vitamin A is a proven hepatotoxic agent which can lead to liver injury ranging from acute hepatitis to cirrhosis. Here, we present a case of chronic pancreatitis who continued antioxidant therapy unsupervised for 7 years and developed vitamin A-induced acute liver failure, which was treated with prednisolone.

Indexed as

AdultAntioxidantsChemical and Drug Induced Liver InjuryDiagnosis, DifferentialGlucocorticoidsHumansMalePancreatitis, ChronicPrednisoloneVitamin AAntioxidantsGlucocorticoidsPrednisoloneVitamin Acontraindications and precautionsgastrointestinal systemliver diseasepancreatitis

Identifiers

PMID32139453
PMCPMC7059506
OpenAlexW3010067256

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.