Evidence map›Paper›PMID 32139427›Full record

ArticleAJNR. American journal of neuroradiology2020

MRI Vessel Wall Imaging after Intra-Arterial Treatment for Acute Ischemic Stroke.

A Lindenholz, I C van der Schaaf, A G van der Kolk, H B van der Worp, A A Harteveld, L J Kappelle, J Hendrikse

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in AJNR. American journal of neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05912686 (High Dose of Atorvastatin for Preventing Cerebral Vascular Wall Damage in Patients Undergoing Mechanical Thrombectomy), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05912686 phase4unknown statusnot on this mapstarted 2023, after this paper: background citation

High Dose of Atorvastatin for Preventing Cerebral Vascular Wall Damage in Patients Undergoing Mechanical Thrombectomy

TypeinterventionalSponsorZhongda HospitalRan2023 to 2026Enrolled162ConditionsMechanical Thrombectomy, Acute Ischemic StrokeArmsAtorvastatin 80mg, Atorvastatin 20mg
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

A LindenholzFrom the Departments of Radiology (A.L., I.C.v.d.S., A.G.v.d.K., A.A.H., J.H.) A.Lindenholz@umcutrecht.nl.ORCID 0000-0002-5333-5723
I C van der SchaafFrom the Departments of Radiology (A.L., I.C.v.d.S., A.G.v.d.K., A.A.H., J.H.).ORCID 0000-0002-2588-264X
A G van der KolkFrom the Departments of Radiology (A.L., I.C.v.d.S., A.G.v.d.K., A.A.H., J.H.).ORCID 0000-0002-8267-8848
H B van der WorpNeurology and Neurosurgery (H.B.v.d.W., L.J.K.), University Medical Center Utrecht, Utrecht, the Netherlands.ORCID 0000-0001-9891-2136
A A HarteveldFrom the Departments of Radiology (A.L., I.C.v.d.S., A.G.v.d.K., A.A.H., J.H.).ORCID 0000-0002-3379-0710
L J KappelleNeurology and Neurosurgery (H.B.v.d.W., L.J.K.), University Medical Center Utrecht, Utrecht, the Netherlands.ORCID 0000-0001-8665-6630
J HendrikseFrom the Departments of Radiology (A.L., I.C.v.d.S., A.G.v.d.K., A.A.H., J.H.).ORCID 0000-0001-6384-6140
Anna Needs Neuroblastoma Answers · USUniversity Medical Center Utrecht · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeVessel wall imaging is increasingly performed in the diagnostic work-up of patients with ischemic stroke. The aim of this study was to compare vessel wall enhancement after intra-arterial thrombosuction with that in patients not treated with thrombosuction. MATERIALS AND

methodsFrom 2009 to 2017, forty-nine patients with an ischemic stroke underwent 7T MR imaging within 3 months after symptom onset as part of a prospective intracranial vessel wall imaging study. Fourteen of these patients underwent intra-arterial treatment using thrombosuction (intra-arterial treatment group). In the intra-arterial treatment group, vessel walls were evaluated for major vessel wall changes. All patients underwent pre- and postcontrast vessel wall imaging to assess enhancing foci of the vessel wall using coregistered subtraction images. A Wilcoxon signed rank test was performed to test for differences.

resultsIn the intra-arterial treatment group, 11 of 14 patients (79%) showed vessel wall enhancement compared with 17 of 35 patients without intra-arterial treatment (49%). In the intra-arterial treatment group, more enhancing foci were detected on the ipsilateral side (

conclusionsPatients with intra-arterial treatment by means of thrombosuction showed more (concentric) enhancing foci of the vessel wall ipsilateral compared with contralateral to the treated artery than the patients without intra-arterial treatment, suggesting reactive changes of the vessel wall. This finding should be taken into account when assessing vessel wall MR images in patients with stroke.

Indexed as

AdultAgedBrain IschemiaCerebral ArteriesEndovascular ProceduresFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedNeuroimagingProspective StudiesStrokeThrombectomy

Identifiers

PMID32139427
PMCPMC7144656
OpenAlexW3009745549

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.